Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2688262 | 0.81 | CHRM2 (0.35) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL2688261 | 0.81 | CHRM2 (0.35) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL2688263 | 0.81 | CHRM2 (0.35) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL12446042 | 0.80 | CHRM2 (0.40) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL12446592 | 0.80 | CHRM2 (0.40) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL12446002 | 0.80 | CHRM2 (0.40) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL19725575 | 0.80 | CHRM2 (0.40) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL13820561 | 0.80 | CHRM2 (0.40) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL22006156 | 0.77 | CHRM2 (0.47) | CHRM2CHRM1CYP2D6MEN1KMT2A | |
| SCHEMBL17807032 | 0.77 | CHRM2 (0.47) | CHRM2CHRM1CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1426352-A2 | Intermediates for the sythesis of vitamin D and steroid derivatives | The Trustees of Columbia University in the City of New York (US) | 2004-06-09 | — | — | EP | disclosed |
| US-6399767-B1 | COMPOUND CONTAINING OXIRANE RING | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2002-06-04 | — | — | US | disclosed |