Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12446042 | 1.00 | CHRM2 (0.40) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL12446592 | 1.00 | CHRM2 (0.40) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL22006156 | 0.89 | CHRM2 (0.47) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL13079825 | 0.89 | CHRM2 (0.47) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL17807032 | 0.89 | CHRM2 (0.47) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL28522654 | 0.89 | CHRM2 (0.47) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL10064089 | 0.81 | ALDH1A1 (0.34) | — | |
| SCHEMBL25036558 | 0.81 | CHRM2 (0.41) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL6898147 | 0.80 | CHRM2 (0.35) | CHRM2CHRM1KMT2AMEN1CYP2D6 | |
| SCHEMBL19725575 | 0.79 | CHRM2 (0.40) | CHRM2CHRM1KMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097717-A1 | SYNTHESIS OF BICYCLIC COMPOUNDS AND METHOD FOR THEIR USE AS THERAPEUTIC AGENTS | UNIVERSITY OF VICTORIA INNOVATION AND DEVELOPMENT CORPORATION (CA) | 2011-08-18 | — | — | WO | disclosed |