Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6259562 | 0.93 | TSHR (0.37) | HRH3TSHRMEN1THRBHTT | |
| SCHEMBL6255271 | 0.87 | HRH3 (0.38) | HRH3TSHRMEN1THRBHTT | |
| SCHEMBL7057042 | 0.85 | HRH3 (0.39) | HRH3TSHRMEN1THRBHTT | |
| SCHEMBL6254561 | 0.84 | TSHR (0.37) | HRH3TSHRMEN1THRBHTT | |
| SCHEMBL6258539 | 0.84 | MEN1 (0.38) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL25884127 | 0.83 | HRH3 (0.46) | HRH3TSHR | |
| SCHEMBL6942885 | 0.83 | HRH3 (0.40) | HRH3TSHRMEN1THRBHTT | |
| SCHEMBL6435837 | 0.83 | HRH3 (0.38) | HRH3TSHRMEN1THRBHTT | |
| SCHEMBL6255265 | 0.82 | MEN1 (0.37) | HRH3TSHRMEN1THRBHTT | |
| SCHEMBL6260564 | 0.81 | TSHR (0.39) | HRH3TSHRMEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004529069-A | — | — | 2004-09-24 | — | — | JP | claimed |
| EP-1351916-A2 | ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2003-10-15 | — | — | EP | claimed |
| WO-2002030863-A2 | ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | claimed |