Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.72 |
| ▸ | PI4KA | P42356 | 2/20 | 0.72 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.72 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.72 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.72 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.72 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.72 |
| ▸ | DPP4 | P27487 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.72 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.72 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.72 |
| ▸ | GAPDH | P04406 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | STAT6 | P42226 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.72 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5559352 | 1.00 | ADORA3 (0.72) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL29722344 | 1.00 | ADORA3 (0.72) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL6898569 | 0.93 | ADORA3 (0.71) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL29705802 | 0.93 | ADORA3 (0.71) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL6898572 | 0.93 | ADORA3 (0.71) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL23466944 | 0.93 | ADORA3 (0.71) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL13777063 | 0.92 | ADORA3 (0.72) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28804979 | 0.91 | ADORA3 (0.75) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL6892950 | 0.91 | ADORA3 (0.68) | ADORA3ADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL29705721 | 0.91 | ADORA3 (0.68) | ADORA3ADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1418179-A2 | Compositions and methods for detecting and modulating rna activity and gene expression | ISIS PHARMACEUTICALS, INC. (US) | 2004-05-12 | — | — | EP | disclosed |
| US-5773603-A | ADENOSINE DEAMINASE INHIBITOR | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0601322-A2 | Adenosindeaminase inhibitor | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0269574-B1 | NOVEL ADENOSINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS AN ACTIVE INGREDIENT | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4843066-A | HYPOTENSIVE AGENTS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |