Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699834 | 0.89 | SMPD1 (0.36) | SMPD1 | |
| SCHEMBL6503075 | 0.89 | SMPD1 (0.30) | SMPD1 | |
| SCHEMBL12953253 | 0.84 | SMPD1 (0.39) | SMPD1 | |
| SCHEMBL6503879 | 0.83 | SMPD1 (0.40) | SMPD1 | |
| SCHEMBL7169209 | 0.83 | SMPD1 (0.36) | SMPD1 | |
| SCHEMBL7055514 | 0.82 | — | — | |
| SCHEMBL6504573 | 0.82 | SMPD1 (0.42) | SMPD1 | |
| SCHEMBL7210763 | 0.78 | SMPD1 (0.39) | SMPD1 | |
| SCHEMBL6502059 | 0.77 | GRM4 (0.32) | SMPD1 | |
| SCHEMBL7210769 | 0.77 | SMPD1 (0.32) | SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6673780-B2 | SUCH AS 4-(4-(3-HYDROXY-3-METHYL-BUTANE-1-SULFINYLMETHYL)-PHENYLMETHANESULFINYL)-2 -METHYL-BUTAN1-OL FOR TREATING AND PREVENTING CARDIOVASCULAR DISEASES, DYSLIPIDEMIAS, DYSPROTEINEMIAS, AND GLUCOSE METABOLISM DISORDERS | ESPERION THERAPEUTICS, INC. | 2004-01-06 | — | — | US | disclosed |