Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
| ▸ | CTSS | P25774 | 5/20 | 0.51 |
| ▸ | CTSK | P43235 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | IL2 | P60568 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850273 | 1.00 | CA2 (0.61) | CA2ACEPTPN1ITGB3ITGA2B | |
| SCHEMBL15109826 | 1.00 | CA2 (0.61) | CA2ACEPTPN1ITGB3ITGA2B | |
| SCHEMBL1748947 | 0.90 | ACE (0.59) | CA2ACEPTPN1ITGB3ITGA2B | |
| SCHEMBL1311165 | 0.90 | ACE (0.59) | CA2ACEPTPN1ITGB3ITGA2B | |
| SCHEMBL1529592 | 0.90 | ACE (0.59) | CA2ACEPTPN1ITGB3ITGA2B | |
| SCHEMBL7039592 | 0.89 | CA2 (0.52) | CA2ACEPTPN1CTSLCTSS | |
| SCHEMBL5782787 | 0.89 | CA2 (0.52) | CA2ACEPTPN1CTSLCTSS | |
| SCHEMBL29398258 | 0.89 | CA2 (0.51) | CA2ACEPTPN1ITGB3ITGA2B | |
| SCHEMBL15109777 | 0.89 | CA2 (0.51) | CA2ACEPTPN1ITGB3ITGA2B | |
| SCHEMBL27979465 | 0.89 | CA2 (0.51) | CA2ACEPTPN1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830136-B1 | NEW CRYPTOPHYCINS FROM SYNTHESIS | UNIV HAWAII (US) | 2004-10-20 | — | — | EP | disclosed |
| CN-1165337-C | Synthetic cryptophycins | ���Ĵ���ѧ | 2004-09-08 | — | — | CN | disclosed |
| EP-0830136-A4 | NEW CRYPTOPHYCINS FROM SYNTHESIS | UNIV HAWAII (US) | 2001-01-24 | — | — | EP | disclosed |
| CN-1183726-A | Synthetic cryptophycins | UNIV HAWAII (US) | 1998-06-03 | — | — | CN | disclosed |
| EP-0830136-A1 | NEW CRYPTOPHYCINS FROM SYNTHESIS | UNIVERSITY OF HAWAII (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040184-A1 | NEW CRYPTOPHYCINS FROM SYNTHESIS | UNIVERSITY OF HAWAII (US) | 1996-12-19 | — | — | WO | disclosed |