Terephthalamide

Terephthalamide

SCHEMBL689841

C.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 2/20 0.67
TSHR P16473 2/20 0.67
POLB P06746 1/20 0.67
CYP3A4 P08684 1/20 0.67
MAPT P10636 1/20 0.67
CYP2C19 P33261 1/20 0.67
RECQL P46063 1/20 0.67
BLM P54132 1/20 0.67
PMP22 Q01453 1/20 0.67
HSD17B10 Q99714 1/20 0.67
TDP1 Q9NUW8 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
PARP10 Q53GL7 10/20 0.65
PARP4 Q9UKK3 2/20 0.65
PARP15 Q460N3 2/20 0.65
ALDH1A1 P00352 1/20 0.65
KMT2A Q03164 1/20 0.65
PARP14 Q460N5 1/20 0.65
PARP16 Q8N5Y8 1/20 0.65
PARP11 Q9NR21 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL23774 0.96 PARP1 (0.71) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL29102653 0.93 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL28360111 0.93 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL27450033 0.93 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL11512422 0.93 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL15328883 0.93 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL7508927 0.93 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL1087289 0.93 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL1906838 0.93 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT
Terephthalamide SCHEMBL27281597 0.93 PARP1 (0.67) PARP1TSHRPOLBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6156838-A Polyamide resin composition and process for producing the same UNITIKA LTD. (JP) 2000-12-05 US claimed
EP-4299540-A1 GLASS COMPOSITION FOR GLASS FIBER, GLASS FIBER, GLASS FIBER WOVEN FABRIC, AND GLASS-FIBER-REINFORCED RESIN COMPOSITION Nitto Boseki Co., Ltd. (JP) 2024-01-03 EP disclosed
CN-106661324-B Amilan polyamide resin composition and the formed products formed by it 宇部兴产株式会社 2019-08-02 CN disclosed
CN-106661324-A Polyamide resin composition and molded article comprising same 宇部兴产株式会社 2017-05-10 CN disclosed
CN-103467735-B The high temperature polyamide moulding composition strengthened with flat glass fiber EMS专利股份公司 2016-07-13 CN disclosed
EP-1394214-B1 POLYAMIDE RESIN COMPOSITION FOR FUSE DEVICE PACIFIC ENGINEERING CORP (JP) 2012-02-29 EP disclosed
EP-0973609-B1 POLYMER COMPOSITES AND METHODS FOR MAKING AND USING SAME INTEGUMENT TECHNOLOGIES INC (US) 2009-04-15 EP disclosed
EP-1394214-A1 POLYAMIDE RESIN COMPOSITION FOR FUSE DEVICE Pacific Engineering Corporation (JP) 2004-03-03 EP disclosed