Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901465 | 0.98 | KDM4E (0.56) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL12244766 | 0.96 | KDM4E (0.58) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL25650255 | 0.93 | KDM4E (0.52) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL13824881 | 0.92 | KDM4E (0.54) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL20261071 | 0.89 | KDM4E (0.52) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL19726708 | 0.89 | PAOX (0.63) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL23961769 | 0.86 | CYP2D6 (0.44) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL18310182 | 0.85 | KDM4E (0.50) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL19726707 | 0.84 | TDP1 (0.58) | HIF1AKDM4EMAPK1PAOXADRA1A | |
| SCHEMBL8428056 | 0.82 | KDM4E (0.50) | HIF1AKDM4EMAPK1PAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6808716-B2 | N-acetylamino acids, related N-acetyl compounds and their topical use | YU RUEY J (US) | 2004-10-26 | — | — | US | disclosed |
| WO-2004089329-A2 | TOPICAL COMPOSITIONS COMPRISING N-ACETYLAMINO ACIDS OR RELATED N-ACETYL COMPOUNDS | YU RUEY J (US) | 2004-10-21 | — | — | WO | disclosed |
| US-20030229141-A1 | N-acetyl cysteine and its topical use | YU RUEY J (US) | 2003-12-11 | — | — | US | disclosed |
| US-20030198656-A1 | N-acetylamino acids, related N-acetyl compounds and their topical use | YU RUEY J (US) | 2003-10-23 | — | — | US | disclosed |