Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898519 | 0.98 | HIF1A (0.60) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL12244766 | 0.98 | KDM4E (0.58) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL13824881 | 0.94 | KDM4E (0.54) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL20261071 | 0.91 | KDM4E (0.52) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL19726708 | 0.91 | PAOX (0.63) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL23961769 | 0.88 | CYP2D6 (0.44) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL18310182 | 0.87 | KDM4E (0.50) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8428056 | 0.84 | KDM4E (0.50) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL19726659 | 0.83 | KDM4E (0.40) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL19925724 | 0.83 | KDM4E (0.39) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183365-A1 | MACROCYCLES | LUMIPHORE, INC. | 2017-06-29 | — | — | US | disclosed |
| US-20160221971-A1 | DI-MACROCYCLES | LUMIPHORE, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| US-6808716-B2 | N-acetylamino acids, related N-acetyl compounds and their topical use | YU RUEY J (US) | 2004-10-26 | — | — | US | disclosed |
| WO-2004089329-A2 | TOPICAL COMPOSITIONS COMPRISING N-ACETYLAMINO ACIDS OR RELATED N-ACETYL COMPOUNDS | YU RUEY J (US) | 2004-10-21 | — | — | WO | disclosed |
| US-20030229141-A1 | N-acetyl cysteine and its topical use | YU RUEY J (US) | 2003-12-11 | — | — | US | disclosed |
| US-20030198656-A1 | N-acetylamino acids, related N-acetyl compounds and their topical use | YU RUEY J (US) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221971-A1 | DI-MACROCYCLES | DLD, NDC1, MCL1 | KDM4E 4621/4885MAPK1 4795/4885HIF1A 1834/4885 |
| US-20170183365-A1 | MACROCYCLES | HCCS, ABCB7, AURKAIP1 | KDM4E 4482/4885MAPK1 4778/4885HIF1A 1763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.