Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926750 | 0.79 | ACP3 (0.61) | ACP3CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL4189468 | 0.78 | ACP3 (0.55) | ACP3CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL3283005 | 0.78 | ACP3 (0.55) | ACP3CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL6007985 | 0.77 | ALDH1A1 (0.50) | CYP2C9CYP2C19ALDH1A1CYP1A2SLC6A4 | |
| SCHEMBL29090512 | 0.74 | ACP3 (0.51) | ACP3CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL10750280 | 0.74 | ACP3 (0.51) | ACP3CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL3048277 | 0.74 | ACP3 (0.59) | ACP3CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL7239903 | 0.74 | ACP3 (0.51) | ACP3CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5028986 | 0.74 | ACP3 (0.51) | ACP3CYP2C9CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL2321827 | 0.73 | ALDH1A1 (0.60) | ACP3CYP2C9CYP2C19ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6750255-B2 | SUCH AS (R)-N-(1-(1'-NAPHTHYL)ETHYL)-2-(2',5'-DICHOROPHENYL THIO)ETHYLAMINE; FOR STIMULATION OF SECRETION OF PARATHYROID HORMONE | NPS PHARMACEUTICALS, INC. | 2004-06-15 | — | — | US | disclosed |
| US-20030176485-A1 | Calcium receptor active compounds | NPS PHARMACEUTICALS, INC. | 2003-09-18 | — | — | US | disclosed |
| US-20020107406-A1 | Calcium receptor-active compounds | NPS PHARMACEUTICALS, INC. (US) | 2002-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176485-A1 | Calcium receptor active compounds | CASR, CNR1, CALCR | ACP3 2748/4885CYP2C9 1003/4885CYP2C19 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.