Styrene

Styrene

SCHEMBL689868

C=Cc1ccccc1.C=Cc1ccccc1C=C.CC(=CCCO)C(=O)O

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.44
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.38
CYP2C9 P11712 1/20 0.36
KDM4E B2RXH2 1/20 0.35
BACE1 P56817 2/20 0.34
GLA P06280 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PPARG P37231 1/20 0.33
PTGS2 P35354 1/20 0.33
RECQL P46063 1/20 0.33
TBXAS1 P24557 1/20 0.32
PSMD14 O00487 1/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 2/20 0.32
POLB P06746 1/20 0.32
NPC1 O15118 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
FBP1 P09467 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7261213 0.94 AKR1C3 (0.41) AKR1C3ALDH1A1HTTCYP2C9KDM4E
Styrene SCHEMBL5725939 0.94 AKR1C3 (0.49) AKR1C3ALDH1A1TSHRHTTCYP2C9
Styrene SCHEMBL5662638 0.94 AKR1C3 (0.49) AKR1C3ALDH1A1TSHRHTTCYP2C9
Styrene SCHEMBL5340494 0.90 AKR1C3 (0.45) AKR1C3ALDH1A1TSHRHTTCYP2C9
Styrene SCHEMBL829551 0.90 AKR1C3 (0.45) AKR1C3ALDH1A1TSHRHTTCYP2C9
Styrene SCHEMBL8737030 0.86 AKR1C3 (0.41) AKR1C3ALDH1A1TSHRHTTCYP2C9
Styrene SCHEMBL3441339 0.85 AKR1C3 (0.46) AKR1C3ALDH1A1TSHRHTTCYP2C9
Styrene SCHEMBL17080378 0.85 AKR1C3 (0.46) AKR1C3ALDH1A1TSHRHTTCYP2C9
Styrene SCHEMBL21113739 0.83 AKR1C3 (0.39) AKR1C3ALDH1A1TSHRHTTCYP2C9
Styrene SCHEMBL7730624 0.83 AKR1C3 (0.39) AKR1C3ALDH1A1TSHRHTTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1756178-B1 PROCESS FOR MANUFACTURING A COMPOSITE SORBENT MATERIAL FOR CHROMATOGRAPHICAL SEPARATION OF BIOPOLYMERS NEXTTEC GMBH (DE) 2012-02-29 EP disclosed