Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL11433472 | 0.94 | AKR1C3 (0.52) | AKR1C3ALDH1A1TSHRHTTCYP2C9 | |
| Styrene SCHEMBL22399380 | 0.94 | AKR1C3 (0.52) | AKR1C3ALDH1A1TSHRHTTCYP2C9 | |
| Styrene SCHEMBL9630667 | 0.94 | AKR1C3 (0.52) | AKR1C3ALDH1A1TSHRHTTCYP2C9 | |
| Styrene SCHEMBL28105447 | 0.88 | ALDH1A1 (0.45) | AKR1C3ALDH1A1TSHRHTTCYP2C9 | |
| SCHEMBL7747003 | 0.87 | AKR1C3 (0.48) | AKR1C3ALDH1A1HTTCYP2C9KDM4E | |
| Styrene SCHEMBL238869 | 0.87 | AKR1C3 (0.59) | AKR1C3ALDH1A1TSHRHTTCYP2C9 | |
| Styrene SCHEMBL134355 | 0.87 | AKR1C3 (0.59) | AKR1C3ALDH1A1TSHRHTTCYP2C9 | |
| SCHEMBL4865262 | 0.87 | AKR1C3 (0.48) | AKR1C3ALDH1A1HTTCYP2C9KDM4E | |
| Ethylene Glycol SCHEMBL17080383 | 0.86 | AKR1C3 (0.40) | AKR1C3HTTCYP2C9KDM4EGLA | |
| Styrene SCHEMBL689868 | 0.85 | AKR1C3 (0.44) | AKR1C3ALDH1A1TSHRHTTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10457720-B2 | Robust antibody purification | MERCK PATENT GMBH (DE) | 2019-10-29 | — | — | US | claimed |
| US-20170073394-A1 | ROBUST ANTIBODY PURIFICATION | MERCK PATENT GMBH (DE) | 2017-03-16 | — | — | US | claimed |
| EP-3114455-A1 | ROBUST ANTIBODY PURIFICATION | Merck Patent GmbH (DE) | 2017-01-11 | — | — | EP | claimed |
| WO-2015131978-A1 | ROBUST ANTIBODY PURIFICATION | MERCK PATENT GMBH (DE) | 2015-09-11 | — | — | WO | claimed |