Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 13/20 | 0.61 |
| ▸ | MTOR | P42345 | 8/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.61 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.61 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.61 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6900142 | 0.92 | MTOR (0.61) | PIK3CAMTORPIK3CGPIK3CBPIK3C3 | |
| SCHEMBL1913603 | 0.89 | PIK3CA (0.56) | PIK3CAMTORPIK3CGPIK3CBPIK3C3 | |
| SCHEMBL6898715 | 0.86 | MTOR (0.67) | PIK3CAMTORPIK3CGPIK3CBPIK3C3 | |
| SCHEMBL6900336 | 0.86 | MTOR (0.66) | PIK3CAMTORPIK3CGPIK3CBPIK3C3 | |
| SCHEMBL6900031 | 0.86 | PIK3CA (0.56) | PIK3CAMTORPIK3CGPIK3CBPIK3C3 | |
| SCHEMBL6898688 | 0.82 | MTOR (0.67) | PIK3CAMTORPIK3CGPIK3CBPIK3C3 | |
| SCHEMBL6899720 | 0.81 | MTOR (0.63) | PIK3CAMTORPIK3CGPIK3CBPIK3C3 | |
| SCHEMBL6899723 | 0.80 | MTOR (0.66) | PIK3CAMTORPIK3CGPIK3CBPIK3C3 | |
| SCHEMBL1913668 | 0.78 | MTOR (0.80) | PIK3CAMTORPIK3CGPIK3CBPIK3C3 | |
| SCHEMBL6900063 | 0.78 | MTOR (0.59) | PIK3CAMTORPIK3CGPIK3CBPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078795-A1 | BRIDGED MORPHOLINO SUBSTITUTED PURINES | S*BIO PTE LTD (SG) | 2011-06-30 | — | — | WO | disclosed |