Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 9/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.66 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.66 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.66 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.66 |
| ▸ | PI4KA | P42356 | 3/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 4/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.34 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.34 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.34 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898715 | 0.99 | MTOR (0.67) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898696 | 0.89 | MTOR (0.57) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6899723 | 0.88 | MTOR (0.66) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6899720 | 0.88 | MTOR (0.63) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898688 | 0.86 | MTOR (0.67) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6900142 | 0.86 | MTOR (0.61) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6898833 | 0.86 | PIK3CA (0.61) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL7955199 | 0.84 | FLT3 (0.53) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6900063 | 0.84 | MTOR (0.59) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 | |
| SCHEMBL6899131 | 0.83 | PIK3CA (0.65) | MTORPIK3CAPIK3CBPIK3CGPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078795-A1 | BRIDGED MORPHOLINO SUBSTITUTED PURINES | S*BIO PTE LTD (SG) | 2011-06-30 | — | — | WO | disclosed |