SCHEMBL6899227

SCHEMBL6899227

CC(C)C(=O)OC(N)C=O

nearest known ligand 0.30

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30
GABRA2 P47869 2/20 0.30
GABRB2 P47870 2/20 0.30
GABRA4 P48169 2/20 0.30
GABRE P78334 2/20 0.30
GABRA6 Q16445 2/20 0.30
GABRG1 Q8N1C3 2/20 0.30
GABRG3 Q99928 2/20 0.30
GABRQ Q9UN88 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14645902 0.79 TSHR (0.34)
SCHEMBL8678989 0.75
SCHEMBL14218181 0.75 ELANE (0.34)
SCHEMBL19361146 0.74
Hydrochloric Acid SCHEMBL3507717 0.72 TSHR (0.33)
SCHEMBL11396697 0.70
SCHEMBL2678654 0.70 TSHR (0.33)
SCHEMBL295903 0.68
SCHEMBL13647266 0.68 TSHR (0.38)
SCHEMBL28333588 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3038992-B1 NOVEL FIBERS, METHODS FOR THEIR PREPARATION AND USE IN THE MANUFACTURE OF REINFORCED ELEMENTS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2019-10-30 EP disclosed
CN-105492406-B New fiber, preparation method and the purposes in manufacture reinforcing element 建筑研究和技术有限公司 2018-11-16 CN disclosed
US-10065887-B2 Fibers, methods for their preparation and use in the manufacture of reinforced elements CONSTRUCTION RESEARCH & TECHNOLOGY, GMBH (DE) 2018-09-04 US disclosed
US-20180022980-A1 USE OF CSH-SEED MODIFIED FIBERS IN OIL FIELD APPLICATIONS BASF CONSTRUCTION SOLUTIONS GMBH (DE) 2018-01-25 US disclosed
EP-3262009-A1 USE OF CSH-SEED MODIFIED FIBERS IN OIL FIELD APPLICATIONS BASF SE (DE) 2018-01-03 EP disclosed
WO-2016135182-A1 USE OF CSH-SEED MODIFIED FIBERS IN OIL FIELD APPLICATIONS BASF SE (DE) 2016-09-01 WO disclosed
US-20160194245-A1 NOVEL FIBERS, METHODS FOR THEIR PREPARATION AND USE IN THE MANUFACTURE OF REINFORCED ELEMENTS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2016-07-07 US disclosed
EP-3038992-A1 NOVEL FIBERS, METHODS FOR THEIR PREPARATION AND USE IN THE MANUFACTURE OF REINFORCED ELEMENTS Construction Research & Technology GmbH (DE) 2016-07-06 EP disclosed
CN-105492406-A Novel fibers, methods for their preparation and use in the manufacture of reinforced elements CONSTRUCTION RESEARCH & TECHNOLOGY GMBH 2016-04-13 CN disclosed
EP-2842921-A1 Novel fibers, methods for their preparation and use in the manufacture of reinforced elements Construction Research & Technology GmbH (DE) 2015-03-04 EP disclosed
US-20040019046-A1 Phenylacetamido-pyrazole derivatives and their use as antitumor agents PHARMACIA ITALIA SPA (IT) 2004-01-29 US disclosed
EP-1345909-A1 PHENYLACETAMIDO-PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS Pharmacia Italia S.p.A. (IT) 2003-09-24 EP disclosed
WO-2002048114-A1 PHENYLACETAMIDO- PYRAZOLE DERIVATIVES AND THEIR USE AS ANTITUMOR AGENTS PHARMACIA ITALIA S.P.A. (IT) 2002-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040019046-A1 Phenylacetamido-pyrazole derivatives and their use as antitumor agents DCK, CCNK, CDK2 GABRP 2720/4885GABRD 4062/4885GABRA1 4068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.