SCHEMBL689927

SCHEMBL689927

O=C(O)c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.69
ALDH1A1 P00352 2/20 0.69
TSHR P16473 3/20 0.59
DAO P14920 1/20 0.59
NAPRT Q6XQN6 1/20 0.59
TP53 P04637 1/20 0.57
SRD5A2 P31213 2/20 0.56
CES2 O00748 1/20 0.56
CES1 P23141 1/20 0.56
LMNA P02545 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
PKM P14618 1/20 0.53
RARB P10826 1/20 0.50
RARG P13631 1/20 0.50
RXRA P19793 1/20 0.50
RXRB P28702 1/20 0.50
RXRG P48443 1/20 0.50
TRPA1 O75762 1/20 0.50
KDM4E B2RXH2 1/20 0.50
APEX1 P27695 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15220060 0.93 TSHR (0.67) HPGDALDH1A1TSHRDAONAPRT
SCHEMBL71112 0.93 TSHR (0.67) HPGDALDH1A1TSHRDAONAPRT
SCHEMBL15220063 0.93 TSHR (0.67) HPGDALDH1A1TSHRDAONAPRT
SCHEMBL9459884 0.90 TSHR (0.63) HPGDALDH1A1TSHRDAONAPRT
Barium SCHEMBL9452526 0.90 TSHR (0.63) HPGDALDH1A1TSHRDAONAPRT
Hydrochloric Acid SCHEMBL7138094 0.90 TSHR (0.63) HPGDALDH1A1TSHRDAONAPRT
SCHEMBL9786354 0.86 HPGD (0.59) HPGDALDH1A1TSHRDAONAPRT
SCHEMBL3282737 0.86 HPGD (0.69) HPGDALDH1A1SRD5A2CES2CES1
SCHEMBL1447749 0.86 HPGD (0.66) HPGDALDH1A1TSHRDAONAPRT
Benzoic Acid SCHEMBL10528690 0.85 CA12 (0.60) HPGDALDH1A1TSHRDAONAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102448978-A Novel Glucocorticoid Receptor Agonists PFIZER LTD 2012-05-09 CN claimed
WO-2009140215-A2 METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS GERAGHTY, ERIN (US) 2009-11-19 WO claimed
CN-119143677-A Preparation method of fenticonazole or nitrate thereof 浙江东亚药业股份有限公司 2024-12-17 CN disclosed
US-11774853-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-03 US disclosed
US-11649322-B2 Sulfur-stabilized copolycarbonates and articles formed therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-16 US disclosed
US-11649322-B2 Sulfur-stabilized copolycarbonates and articles formed therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2023-05-16 US disclosed
US-11415887-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-08-16 US disclosed
US-11187980-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-11-30 US disclosed
US-20210302838-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-09-30 US disclosed
WO-2021112957-A1 ARYL BENZOFURANONE- STABILIZED POLYCARBONATE COMPOSITIONS, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-06-10 WO disclosed
CN-107129458-B Carbazole oxime ester compound and synthesis method and application thereof 江苏和成新材料有限公司 2021-02-09 CN disclosed
CN-1310621-A Substituted anilide compounds and methods SMITHKLINE BEECHAM CORP (US) 2001-08-29 CN disclosed
EP-1100485-A1 SUBSTITUTED ANILIDE COMPOUNDS AND METHODS SMITHKLINE BEECHAM CORPORATION (US) 2001-05-23 EP disclosed
WO-2000006146-A9 SUBSTITUTED ANILIDE COMPOUNDS AND METHODS SMITHKLINE BEECHAM CORP (US) 2000-08-03 WO disclosed
CN-1052725-C Tricyclic vasopressin antagonists AMERICAN CYANAMID CO (US) 2000-05-24 CN disclosed
WO-2000006146-A1 SUBSTITUTED ANILIDE COMPOUNDS AND METHODS SMITHKLINE BEECHAM CORPORATION (US) 2000-02-10 WO disclosed
US-5780471-A Tricyclic benzazepine vasopressin antagonists AMERICAN CYANAMID COMPANY (US) 1998-07-14 US disclosed
CN-1178532-A Tricyclic vasopressin antagonists AMERICAN CYANAMID CO (US) 1998-04-08 CN disclosed
WO-1996022292-A1 TRICYCLIC VASOPRESSIN ANTAGONISTS AMERICAN CYANAMID COMPANY (US) 1996-07-25 WO disclosed
US-5521173-A TREATING DISEASES CHARACTERIZED BY EXCESS RENAL REABSORPTION OF WATER AMERICAN HOME PRODUCTS CORPORATION (US) 1996-05-28 US disclosed