Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031926 | 0.74 | PTGDR2 (0.37) | SLC6A2SLC6A4PTGDR2SLC6A3LMNA | |
| SCHEMBL20562354 | 0.70 | PTGDR2 (0.40) | SLC6A2SLC6A4PTGDR2PSEN1PSEN2 | |
| SCHEMBL31393933 | 0.70 | PTGDR2 (0.37) | SLC6A2SLC6A4PTGDR2PSEN1PSEN2 | |
| SCHEMBL9033192 | 0.70 | NPC1 (0.36) | SLC6A2SLC6A4PTGDR2LMNAHTT | |
| SCHEMBL29417721 | 0.69 | PTGDR2 (0.48) | SLC6A2SLC6A4PTGDR2SLC6A3LMNA | |
| SCHEMBL795719 | 0.69 | PTGDR2 (0.48) | SLC6A2SLC6A4PTGDR2SLC6A3LMNA | |
| SCHEMBL30352488 | 0.69 | PYCR1 (0.47) | SLC6A2SLC6A4PTGDR2LMNAMAPT | |
| SCHEMBL15720088 | 0.69 | PTGDR2 (0.44) | SLC6A2SLC6A4PTGDR2SLC6A3LMNA | |
| SCHEMBL6673 | 0.69 | PYCR1 (0.47) | SLC6A2SLC6A4PTGDR2LMNAMAPT | |
| SCHEMBL754025 | 0.69 | KDM4E (0.41) | SLC6A2SLC6A4PTGDR2SLC6A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900241-B1 | SILYL LINKER FOR SOLID PHASE ORGANIC SYNTHESIS OF ARYL-CONTAINING MOLECULES | SMITHKLINE BEECHAM CORP (US) | 2004-01-28 | — | — | EP | disclosed |
| EP-0900241-A4 | SILYL LINKER FOR SOLID PHASE ORGANIC SYNTHESIS OF ARYL-CONTAINING MOLECULES | SMITHKLINE BEECHAM CORP (US) | 2002-10-09 | — | — | EP | disclosed |
| US-6127489-A | Silyl linker for solid phase organic synthesis of aryl-containing molecules | SMITHKLINE BEECHAM CORPORATION (US) | 2000-10-03 | — | — | US | disclosed |
| EP-0900241-A1 | SILYL LINKER FOR SOLID PHASE ORGANIC SYNTHESIS OF ARYL-CONTAINING MOLECULES | SMITHKLINE BEECHAM CORPORATION (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997044367-A1 | SILYL LINKER FOR SOLID PHASE ORGANIC SYNTHESIS OF ARYL-CONTAINING MOLECULES | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-27 | — | — | WO | disclosed |