⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18531562 | 0.76 | — | — | |
| SCHEMBL21401201 | 0.71 | — | — | |
| SCHEMBL19954013 | 0.67 | — | — | |
| SCHEMBL31509387 | 0.60 | LMNA (0.33) | — | |
| SCHEMBL12656431 | 0.58 | — | — | |
| SCHEMBL5739240 | 0.57 | — | — | |
| SCHEMBL14879296 | 0.56 | — | — | |
| SCHEMBL19648440 | 0.56 | — | — | |
| SCHEMBL18596207 | 0.56 | — | — | |
| SCHEMBL24612971 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011030068-A1 | USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS FOR THE APPLICATION THEREOF AS A MEDICAMENT FOR THE TREATMENT OF PARKINSON'S DISEASE | LABORATOIRES FOURNIER SA (FR) | 2011-03-17 | — | — | WO | disclosed |