Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 3/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.38 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16255674 | 0.83 | L3MBTL4 (0.50) | S1PR4KDM4EALDH1A1GAALMNA | |
| SCHEMBL18704596 | 0.83 | S1PR4 (0.54) | S1PR4KDM4EALDH1A1GAAPTGDR2 | |
| SCHEMBL12139658 | 0.81 | KDM4E (0.48) | S1PR4KDM4EALDH1A1GAALMNA | |
| SCHEMBL12142095 | 0.81 | S1PR1 (0.45) | S1PR4KDM4EALDH1A1GAALMNA | |
| SCHEMBL2147319 | 0.80 | S1PR4 (0.53) | S1PR4KDM4EPTGDR2LMNASMN1; SMN2 | |
| SCHEMBL2146473 | 0.80 | S1PR4 (0.51) | S1PR4KDM4EPTGDR2USP28USP25 | |
| SCHEMBL1630832 | 0.80 | S1PR4 (0.51) | S1PR4PTGDR2USP28USP25 | |
| SCHEMBL8236376 | 0.79 | S1PR4 (0.50) | S1PR4ALDH1A1GAAPTGDR2LMNA | |
| SCHEMBL2950931 | 0.79 | S1PR1 (0.55) | S1PR4PTGDR2LMNASMN1; SMN2RAB9A | |
| SCHEMBL1630895 | 0.78 | S1PR4 (0.50) | S1PR4KDM4EPTGDR2USP28USP25 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086125-A1 | 1H-[1,2,3]TRIAZOLO[4,5-c]PYRIDINE-4-CARBONITRILE DERIVATIVES | N.V. ORGANON (NL) | 2011-07-21 | — | — | WO | disclosed |