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Sugi Predict / Targets / L3MBTL4

L3MBTL4

Lethal(3)malignant brain tumor-like protein 4 · Q8NA19 · L3MBTL4 on Sugi Atlas →

4,182 patent compounds predicted against L3MBTL4, 3,104 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL1447776 SCHEMBL1447776 0.68 3/20
SCHEMBL1085239 SCHEMBL1085239 0.61 3/20
SCHEMBL1420752 SCHEMBL1420752 0.60 3/20
SCHEMBL1085145 SCHEMBL1085145 0.58 3/20
SCHEMBL1085278 SCHEMBL1085278 0.58 3/20
SCHEMBL1085504 SCHEMBL1085504 0.57 3/20
SCHEMBL1085624 SCHEMBL1085624 0.57 3/20
SCHEMBL1420053 SCHEMBL1420053 0.52 3/20
SCHEMBL1812564 SCHEMBL1812564 0.49 3/20
SCHEMBL1085070 SCHEMBL1085070 0.46 3/20
SCHEMBL764630 SCHEMBL764630 0.84 2/20
SCHEMBL95490 SCHEMBL95490 0.82 2/20
SCHEMBL3030683 SCHEMBL3030683 0.79 2/20
SCHEMBL590136 SCHEMBL590136 0.79 2/20
SCHEMBL1430650 SCHEMBL1430650 0.73 2/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL725466) 0.71 2/20
SCHEMBL1449079 SCHEMBL1449079 0.69 2/20
SCHEMBL1449083 SCHEMBL1449083 0.69 2/20
SCHEMBL1735171 SCHEMBL1735171 0.69 2/20
Hydrochloric Acid Hydrochloric Acid (SCHEMBL722840) 0.69 2/20

Clinical trials — most relevant to L3MBTL4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial Carcinoma PHASE2COMPLETED
PhII 5-Azacytidine Plus Valproic Acid and Eventually Atra in Intermediate II and High Risk MDS PHASE2COMPLETED
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN) nanUNKNOWN
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome nanRECRUITING
Association of SNPs in Long Intergenic Noncoding RNA 00511 (LINC00511) With Breast Cancer Among the Egyptian Population nanCOMPLETED
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
SMN Circular RNAs as Potential Biomarkers for the Therapeutic Response to Nusinersen in Spinal Muscular Atrophy Patients nanUNKNOWN
Sperm Epigenome in Hodgkin Lymphoma nanNOT_YET_RECRUITING
The Value of circRNAs (hsa_circ_0004001) in Early Diagnosis of HCC nanUNKNOWN
Establishment of Human Cellular Disease Models for Wilson Disease nanCOMPLETED
Impact of Weight Loss on the Human Sperm Epitranscriptome nanACTIVE_NOT_RECRUITING
Patient's Derived Organoids for Drug Screening in Glioblastoma nanNOT_YET_RECRUITING
Role of SF3B1 Mutation in Assessment of Acute and Chronic Lymphatic Leukemia nanNOT_YET_RECRUITING
Viral and Epigenetic Influences in CRSwNP nanACTIVE_NOT_RECRUITING
Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact nanUNKNOWN
MicroRNA-1 (miRNA-1) and MicroRNA-133a (miRNA-133a) Levels After Acute Exercise in Ultimate Frisbee Athletes nanUNKNOWN
Diagnosis of RSTS: Identification of the Acetylation Profiles as Epigenetic Markers for Assessing Causality of CREBBP and EP300 Variants. nanUNKNOWN
LINC00511/miR-185-3p Axis and miR-301a-3p Markers for Breast Cancer Diagnosis nanCOMPLETED
MicroRNAs and Cytokines in Peri-Implantitis Tissue nanUNKNOWN
Assessment Of Long Noncoding RNA CCAT1 In Colorectal Cancer Patients nanUNKNOWN
Biocollection in MyeloDysplastic Syndrome (P-MDS) nanRECRUITING
Research on Effects of Acute Consumption of Nuts in Obese Diabetic Women nanRECRUITING
Long Term Monitoring for Risk of Sudden Death nanCOMPLETED
Study of Constitutional Platelet Disease nanUNKNOWN
A Study of Multilocus Methylation Abnormalities in Subjects With Imprinting Disorders nanNOT_YET_RECRUITING
Genetic Factors Affecting the Severity of Beta Thalassemia nanCOMPLETED
X-chromosome Inactivation, Epigenetics and the Transcriptome nanCOMPLETED
Susceptibility Genes in Autism Spectrum Disorders nanCOMPLETED
Studying The Role of Key Epigenetic Mediators in Breast Cancer Patients nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a L3MBTL4 binder may also engage these)

ProteinNameSimilarity
B1B1A0 — 1.000 B1B1A0 →
E1C2V1 — 0.998 E1C2V1 →
L3MBTL3 Lethal(3)malignant brain tumor-like protein 3 0.996 landscape →
A2A5N8 — 0.993 A2A5N8 →
D3ZWK4 — 0.990 D3ZWK4 →
Q5TKR9 — 0.990 Q5TKR9 →
Q1JQD9 — 0.989 Q1JQD9 →
Q8BLB7 — 0.989 Q8BLB7 →
Q8WML3 — 0.988 Q8WML3 →
L3MBTL1 Lethal(3)malignant brain tumor-like protein 1 0.988 landscape →
Q8VCD7 — 0.987 Q8VCD7 →
Q8K3E5 — 0.987 Q8K3E5 →
Q8BZ21 — 0.987 Q8BZ21 →
KDM4B Lysine-specific demethylase 4B 0.987 landscape →
KAT8 Histone acetyltransferase KAT8 0.986 landscape →
Q92613 — 0.986 Q92613 →
Q969R5 — 0.986 Q969R5 →
O70445 — 0.986 O70445 →
P59178 — 0.986 P59178 →
Q5R737 — 0.986 Q5R737 →
Q4V863 — 0.986 Q4V863 →
Q8NEM8 — 0.986 Q8NEM8 →
D3YWQ0 — 0.986 D3YWQ0 →
A4IGY9 — 0.985 A4IGY9 →
Q3MIF2 — 0.985 Q3MIF2 →
Q08BS4 — 0.985 Q08BS4 →
Q63553 — 0.985 Q63553 →
Q28D84 — 0.985 Q28D84 →
Q5XI06 — 0.985 Q5XI06 →
Q6ZUT3 — 0.985 Q6ZUT3 →