Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ERN1 | O75460 | 4/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.46 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310186 | 1.00 | TSHR (0.52) | TSHRERN1TLR2TLR1TLR6 | |
| SCHEMBL27806535 | 0.84 | ERN1 (0.43) | TSHRERN1TLR2TLR1TLR6 | |
| SCHEMBL23491266 | 0.83 | TSHR (0.52) | TSHRGABRA1GABRB2CA1CA2 | |
| SCHEMBL310825 | 0.82 | GABRA1 (0.61) | TSHRERN1TLR2TLR1TLR6 | |
| SCHEMBL5837362 | 0.82 | TSHR (0.53) | TSHRGABRA1GABRB2LMNABLM | |
| SCHEMBL561299 | 0.81 | TSHR (0.68) | TSHRGABRA1GABRB2CA1CA2 | |
| SCHEMBL560318 | 0.81 | TSHR (0.68) | TSHRGABRA1GABRB2CA1CA2 | |
| SCHEMBL560346 | 0.81 | TSHR (0.68) | TSHRGABRA1GABRB2CA1CA2 | |
| SCHEMBL202738 | 0.81 | TSHR (0.68) | TSHRGABRA1GABRB2CA1CA2 | |
| SCHEMBL9442685 | 0.81 | TSHR (0.44) | TSHRERN1TLR2TLR1TLR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443915-A1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES | Cutanix Corporation (US) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003043621-A1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES | CUTANIX CORPORATION (US) | 2003-05-30 | — | — | WO | disclosed |