Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CD69 | Q07108 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 3/20 | 0.33 |
| ▸ | CD14 | P08571 | 3/20 | 0.33 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901135 | 0.79 | POLB (0.41) | CYP2D6ELANECD69TSHRCYP3A4 | |
| SCHEMBL6904879 | 0.73 | MAPT (0.43) | ELANECD69ALDH1A1CYP3A4HPGD | |
| SCHEMBL15822204 | 0.72 | CYP1A2 (0.36) | HIF1ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3682913 | 0.72 | ALDH1A1 (0.33) | HIF1ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5410180 | 0.71 | AHR (0.34) | HIF1ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6907158 | 0.71 | POLB (0.34) | ELANECD69TSHRHSD17B10ALDH1A1 | |
| SCHEMBL27706470 | 0.69 | ALDH1A1 (0.35) | HIF1ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3888554 | 0.69 | ALDH1A1 (0.35) | HIF1ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30430052 | 0.69 | ALDH1A1 (0.35) | HIF1ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1319760 | 0.68 | HIF1A (0.33) | HIF1ACYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |