SCHEMBL6900249

SCHEMBL6900249

O=Cc1cc(I)cc(I)c1I

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.61
TTR P02766 1/20 0.36
MCL1 Q07820 1/20 0.32
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TPMT P51580 1/20 0.31
PKM P14618 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16553587 0.77 ERN1 (0.41) ERN1MCL1MEN1LMNATHRB
SCHEMBL20670553 0.76 ERN1 (0.57) ERN1TTRMCL1
SCHEMBL1527177 0.76 ERN1 (1.00) ERN1TTRCYP1A2CYP2C9HIF1A
SCHEMBL32690998 0.75 ERN1 (0.40) ERN1TTRCYP1A2CYP2C9HIF1A
SCHEMBL6903290 0.70 ERN1 (0.50) ERN1TTRMEN1KMT2ATDP1
SCHEMBL95555 0.70 ERN1 (0.56) ERN1MCL1MEN1LMNATHRB
Formaldehyde SCHEMBL28061059 0.69 TTR (0.45) ERN1TTRTPMTPKM
SCHEMBL31005049 0.69 ERN1 (0.48) ERN1MCL1MEN1LMNATHRB
SCHEMBL22897458 0.67 ERN1 (0.57) ERN1
SCHEMBL22982394 0.67 ERN1 (0.57) ERN1TTRMCL1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4631532-A1 PREPARATION METHOD FOR EMBOLIZATION MICROSPHERES Shanghai Intervascular MedTech Co., Ltd. (CN) 2025-10-15 EP claimed
WO-2024146444-A1 PREPARATION METHOD FOR EMBOLIZATION MICROSPHERES 上海拓脉医疗科技有限公司 2024-07-11 WO claimed
CN-118286496-A Preparation method of embolism microsphere 上海拓脉医疗科技有限公司 2024-07-05 CN claimed
WO-2024017165-A1 METHOXYPOLYETHYLENE GLYCOL-POLY(LACTIC-CO-GLYCOLIC ACID)-POLYLYSINE-BASED DEVELOPING POROUS MICROSPHERE, PREPARATION METHOD, AND USE 森心(上海)科技有限公司 2024-01-25 WO claimed
CN-117323459-A Developable embolism microsphere and preparation method and application thereof 至微(深圳)医学科技有限公司 2024-01-02 CN claimed
CN-115487342-B Self-developing absorbable embolism microsphere and preparation method thereof 海南百迈科医疗科技股份有限公司 2023-11-24 CN claimed
CN-116440315-A Multi-mode developed gelatin sponge microsphere and preparation method thereof 海南百迈科医疗科技股份有限公司 2023-07-18 CN claimed
CN-116251225-A Developing embolism microsphere and processing method thereof 科睿驰(深圳)医疗科技发展有限公司 2023-06-13 CN claimed
EP-3492110-B1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LTD (GB) 2023-03-08 EP claimed
CN-110950981-B Radiopaque polymers 生物兼容英国有限公司 2023-02-17 CN claimed
EP-3041515-A1 RADIOPAQUE POLYMERS Biocompatibles Uk Ltd. (GB) 2016-07-13 EP claimed
US-20160193367-A1 Imageable Polymers BIOCOMPATIBLES UK LTD (GB) 2016-07-07 US claimed
CN-105517582-A Imageable polymers BIOCOMPATIBLES UK LTD 2016-04-20 CN claimed
CN-105517581-A Radiopaque polymers BIOCOMPATIBLES UK LTD 2016-04-20 CN claimed
WO-2015033093-A9 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LTD (GB) 2016-04-07 WO claimed
US-20150110722-A1 IMAGEABLE POLYMERS Boston Scientific Medical Device Limited (IE) 2015-04-23 US claimed
WO-2015033093-A1 RADIOPAQUE POLYMERS BIOCOMPATIBLES UK LTD (GB) 2015-03-12 WO claimed
WO-2015033092-A1 IMAGEABLE POLYMERS BIOCOMPATIBLES UK LTD (GB) 2015-03-12 WO claimed
EP-1390336-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2004-02-25 EP claimed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150110722-A1 IMAGEABLE POLYMERS BRDT, BRD3, BRD2 ERN1 3538/4885TTR 4872/4885MCL1 363/4885
US-20160193367-A1 Imageable Polymers VHL, FLT4, FLT1 ERN1 1786/4885TTR 3226/4885MCL1 582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.