SCHEMBL95555

SCHEMBL95555

O=Cc1ccc(I)cc1I

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 5/20 0.56
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
THRB P10828 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
RAD51 Q06609 1/20 0.39
MCL1 Q07820 1/20 0.36
ALDH1A1 P00352 2/20 0.36
TRIM24 O15164 2/20 0.36
TRIM33 Q9UPN9 2/20 0.36
TSHR P16473 1/20 0.36
PARP1 P09874 1/20 0.34
AR P10275 1/20 0.33
TYR P14679 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5157078 0.82 ERN1 (0.64) ERN1TDP1MEN1LMNATHRB
SCHEMBL5427296 0.78 TDP1 (0.64) ERN1TDP1MEN1LMNATHRB
SCHEMBL11814531 0.78 CDK4 (0.39) ERN1LMNARAD51ALDH1A1PARP1
SCHEMBL152293 0.76 ERN1 (0.69) ERN1RAD51TRIM24TRIM33AR
SCHEMBL2549468 0.76 ERN1 (0.52) ERN1TDP1MEN1LMNATHRB
SCHEMBL24014740 0.76 ERN1 (0.42) ERN1TDP1MEN1LMNATHRB
SCHEMBL1350931 0.76 ERN1 (0.52) ERN1TDP1MEN1LMNATHRB
SCHEMBL8208355 0.76 ALDH1A1 (0.46) ERN1TDP1MEN1LMNATHRB
SCHEMBL10624718 0.76 ERN1 (0.52) ERN1TDP1MEN1LMNATHRB
SCHEMBL15825469 0.76 LMNA (0.40) ERN1TDP1MEN1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150385-A1 Production of Fragments of Lignin with Functional Groups ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2024-05-09 US claimed
EP-4045513-A1 PRODUCTION OF FRAGMENTS OF LIGNIN WITH FUNCTIONAL GROUPS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2022-08-24 EP claimed
CN-114616265-A Production of lignin fragments with functional groups 洛桑联邦理工学院 2022-06-10 CN claimed
WO-2021074210-A1 PRODUCTION OF FRAGMENTS OF LIGNIN WITH FUNCTIONAL GROUPS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2021-04-22 WO claimed
EP-3808755-A1 PRODUCTION OF FRAGMENTS OF LIGNIN WITH FUNCTIONAL GROUPS Ecole Polytechnique Federale De Lausanne (EPFL) EPFL-TTO (CH) 2021-04-21 EP claimed
EP-1390336-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) 2004-02-25 EP claimed
WO-2002096849-A1 METHOD FOR PRODUCING AROMATIC ALDEHYDES AND KETONES BY THE CATALYTIC OXIDATION OF ALKYL-AROMATIC COMPOUNDS DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2002-12-05 WO claimed
US-20240150385-A1 Production of Fragments of Lignin with Functional Groups ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2024-05-09 US disclosed
EP-4045513-A1 PRODUCTION OF FRAGMENTS OF LIGNIN WITH FUNCTIONAL GROUPS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2022-08-24 EP disclosed
CN-114616265-A Production of lignin fragments with functional groups 洛桑联邦理工学院 2022-06-10 CN disclosed
WO-2022070992-A1 METHOD FOR PRODUCING FLUORINATED AROMATIC ALDEHYDE 東レ株式会社 2022-04-07 WO disclosed
WO-2021074210-A1 PRODUCTION OF FRAGMENTS OF LIGNIN WITH FUNCTIONAL GROUPS ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2021-04-22 WO disclosed
EP-3808755-A1 PRODUCTION OF FRAGMENTS OF LIGNIN WITH FUNCTIONAL GROUPS Ecole Polytechnique Federale De Lausanne (EPFL) EPFL-TTO (CH) 2021-04-21 EP disclosed
EP-0434765-A4 TARGETING SUBSTANCE-DIAGNOSTIC/THERAPEUTIC AGENT CONJUGATES HAVING SCHIFF BASE LINKAGES 1992-06-03 EP disclosed
US-5066789-A Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages NEORX CORPORATION (US) 1991-11-19 US disclosed
EP-0434765-A1 TARGETING SUBSTANCE-DIAGNOSTIC/THERAPEUTIC AGENT CONJUGATES HAVING SCHIFF BASE LINKAGES. NEORX CORP (US) 1991-07-03 EP disclosed
US-4997845-A β-alkylmelatonins as ovulation inhibitors ELI LILLY AND COMPANY (US) 1991-03-05 US disclosed
WO-1990003401-A1 TARGETING SUBSTANCE-DIAGNOSTIC/THERAPEUTIC AGENT CONJUGATES HAVING SCHIFF BASE LINKAGES NEORX CORPORATION (US) 1990-04-05 WO disclosed
EP-0281242-A1 Beta-alkylmelatonins ELI LILLY AND COMPANY (US) 1988-09-07 EP disclosed
US-4087444-A Amides as ovulation inhibitors ELI LILLY AND COMPANY (US) 1978-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150385-A1 Production of Fragments of Lignin with Functional Groups DCXR, LCT, GUSB ERN1 2703/4885TDP1 3266/4885MEN1 4877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.