Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6438925 | 0.83 | FBP1 (0.52) | FBP1AKR1C3MAPTRAB9ANPC1 | |
| SCHEMBL13997261 | 0.83 | AKR1C3 (0.52) | FBP1AKR1C3MAPTRAB9AALDH1A1 | |
| SCHEMBL4704674 | 0.78 | FBP1 (0.48) | FBP1AKR1C3MAPTRAB9ANPC1 | |
| SCHEMBL361951 | 0.74 | MAPT (0.51) | FBP1AKR1C3MAPTRAB9ANPC1 | |
| SCHEMBL1481710 | 0.74 | AKR1C3 (0.61) | FBP1AKR1C3MAPTSMN1; SMN2KMT2A | |
| SCHEMBL211298 | 0.74 | AKR1C3 (0.56) | FBP1AKR1C3MAPTRAB9ANPC1 | |
| SCHEMBL1804114 | 0.74 | AKR1C3 (0.61) | FBP1AKR1C3MAPTSMN1; SMN2KMT2A | |
| SCHEMBL1804115 | 0.74 | AKR1C3 (0.61) | FBP1AKR1C3MAPTSMN1; SMN2KMT2A | |
| SCHEMBL1721350 | 0.74 | AKR1C3 (0.50) | FBP1AKR1C3MAPTRAB9ANPC1 | |
| SCHEMBL1497440 | 0.74 | AKR1C3 (0.56) | FBP1AKR1C3MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481026-A2 | WEATHERABLE STYRENIC BLENDS WITH IMPROVED TRANSLUCENCY | GENERAL ELECTRIC COMPANY (US) | 2004-12-01 | — | — | EP | disclosed |
| EP-1371693-A2 | Damage resistant coatings, films and articles of manufacture containing crosslinked nanoparticles | ROHM AND HAAS COMPANY (US) | 2003-12-17 | — | — | EP | disclosed |
| WO-2003074608-A2 | WEATHERABLE STYRENIC BLENDS WITH IMPROVED TRANSLUCENCY | GENERAL ELECTRIC COMPANY (US) | 2003-09-12 | — | — | WO | disclosed |