SCHEMBL690045

SCHEMBL690045

NCCN=C(N)N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2305729 0.97
Hydrochloric Acid SCHEMBL6151037 0.97
SCHEMBL689587 0.80
Agmatine SCHEMBL195497 0.78
Bromide SCHEMBL11026850 0.78 CYP1A2 (0.79)
Hydrochloric Acid SCHEMBL28414629 0.78 CYP1A2 (0.79)
SCHEMBL15315250 0.76
SCHEMBL6693210 0.76 DHPS (1.00)
SCHEMBL6700147 0.76 DHPS (1.00)
SCHEMBL6698306 0.76 DHPS (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113953522-A Electropositive gold nanocluster and preparation method and application thereof 华南师范大学 2022-01-21 CN claimed
US-6906199-B2 Process for preparing distamycin derivatives PHARMACIA ITALIA S.P.A. (IT) 2005-06-14 US claimed
CN-1190418-C Process for preparing distamycin derivatives PHARMACIA ITALIA SPA (IT) 2005-02-23 CN claimed
EP-1347958-B1 PROCESS FOR PREPARING DISTAMYCIN DERIVATIVES PHARMACIA ITALIA SPA (IT) 2005-01-19 EP claimed
US-20040077550-A1 Process for preparing distamycin derivatives NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2004-04-22 US claimed
CN-1476431-A Process for preparing distamycin derivatives 2004-02-18 CN claimed
EP-1347958-A1 PROCESS FOR PREPARING DISTAMYCIN DERIVATIVES Pharmacia Italia S.p.A. (IT) 2003-10-01 EP claimed
WO-2002044147-A1 PROCESS FOR PREPARING DISTAMYCIN DERIVATIVES PHARMACIA ITALIA S.P.A. (IT) 2002-06-06 WO claimed
WO-2000009115-A1 GRP RECEPTOR LIGANDS SMITHKLINE BEECHAM CORPORATION (US) 2000-02-24 WO claimed
US-12291724-B2 Tumor-infiltrating lymphocytes for adoptive cell therapy H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) 2025-05-06 US disclosed
US-20240133046-A1 REDUCING AGENT COMPOSITION FOR IRON OXIDE AND/OR IRON HYDROXIDE KAO CORPORATION (JP) 2024-04-25 US disclosed
EP-4293137-A1 REDUCING AGENT COMPOSITION FOR IRON OXIDE AND/OR IRON HYDROXIDE Kao Corporation (JP) 2023-12-20 EP disclosed
CN-116867741-A Reducing agent composition for ferric oxide and/or ferric hydroxide 花王株式会社 2023-10-10 CN disclosed
US-11723985-B2 Protein delivery to membranes CYTOSEEK LIMITED (GB) 2023-08-15 US disclosed
EP-0371746-A2 Method of separating proteins UNIVERSITY OF MIAMI (US) 1990-06-06 EP disclosed
US-4906659-A Antibiotic tan-749, its derivatives, production and use thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-03-06 US disclosed
US-4906779-A N,N'-disubstituted guanidines and their use as excitatory amino acid antagonists STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY (US) 1990-03-06 US disclosed
EP-0271829-A2 Delta-hydroxy-beta-lysine derivatives and their production Takeda Chemical Industries, Ltd. (JP) 1988-06-22 EP disclosed
US-4226852-A ALKALINITY, AMMONIA-FREE, GUANIDINE DERIVATIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1980-10-07 US disclosed
US-4186186-A Guanidine accelerators for peroxide hair bleaching compositions HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1980-01-29 US disclosed