⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62013 | 0.80 | — | — | |
| SCHEMBL8164803 | 0.80 | ALDH1A1 (0.53) | — | |
| SCHEMBL126987 | 0.77 | ALDH1A1 (0.50) | — | |
| SCHEMBL29661770 | 0.75 | — | — | |
| SCHEMBL686929 | 0.75 | — | — | |
| SCHEMBL16933963 | 0.72 | ALDH1A1 (0.46) | — | |
| SCHEMBL467333 | 0.72 | — | — | |
| SCHEMBL30548743 | 0.72 | — | — | |
| SCHEMBL8747477 | 0.72 | CYP2A6 (0.43) | — | |
| SCHEMBL21520 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101987842-A | Method for preparing 2-methyl thiophene derivatives | SHANGPHARMA CO LTD | 2011-03-23 | — | — | CN | claimed |
| CN-1205206-C | Asymmetric diaryl ethylene photochromic compound, and its preparing method and use | UNIV TSINGHUA (CN) | 2005-06-08 | — | — | CN | claimed |
| US-20230127914-A1 | RESIST PATTERN FORMATION METHOD | TOKYO OHKA KOGYO CO., LTD. (JP) | 2023-04-27 | — | — | US | disclosed |
| CN-110471257-A | The manufacturing method of photosensitive polymer combination, photosensitive dry film and its manufacturing method, resist film, substrate and plating forming object | TOKYO OHKA KOGYO COMPANY | 2019-11-19 | — | — | CN | disclosed |
| CN-110372550-A | Aryl ether and application thereof | 佩洛通治疗公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105530923-B | Aryl ethers and their use | 佩洛通治疗公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-105530923-A | Aryl ethers and their use | PELOTON THERAPEUTICS INC | 2016-04-27 | — | — | CN | disclosed |
| CN-103328481-A | Inhibitors of notum pectinacetylesterase and methods of their use | LEXICON PHARMACEUTICALS INC | 2013-09-25 | — | — | CN | disclosed |
| CN-101987842-A | Method for preparing 2-methyl thiophene derivatives | SHANGPHARMA CO LTD | 2011-03-23 | — | — | CN | disclosed |
| CN-1856498-A | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LAB (US) | 2006-11-01 | — | — | CN | disclosed |
| CN-1205206-C | Asymmetric diaryl ethylene photochromic compound, and its preparing method and use | UNIV TSINGHUA (CN) | 2005-06-08 | — | — | CN | disclosed |
| CN-1161388-C | Metallocene compounds, process for their preparation and their use in catalytic systems for polymerization of olefins | — | 2004-08-11 | — | — | CN | disclosed |
| US-6746562-B2 | STABLE CROSSLINKED STRUCTURE AT ROOM TEMPERATURE, THEREBY HAVING RUBBER PLASTICITY, SUFFICIENT MELT FLOWABILITY AND REPEATED CROSSLINKING FORMATION AND DISSOCIATION | THE YOKOHAMA RUBBER CO., LTD (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040059060-A1 | Thermo-reversible, crosslinkable elastomer and composition thereof | CHINO KEISUKE (JP) | 2004-03-25 | — | — | US | disclosed |
| CN-1098847-C | Furan-and thiophenecarboxamide derivatives, their preparation and their use as inhibitors of HIV-1 and HIV-1 mutant replication | UNIROYAL CHEM CO INC (US) | 2003-01-15 | — | — | CN | disclosed |
| CN-1347424-A | Metallocene compounds, process for their preparation and their use in catalytic systems for polymerization of olefins | BASELL TECHNOLOGY CO B V (NL) | 2002-05-01 | — | — | CN | disclosed |
| CN-1203596-A | Furan-and thiophenecarbothioamide derivatives, their preparation and their use as inhibitors of replication of HIV-1 and HIV-1 mutants | UNIROYAL CHEM CO INC (US) | 1998-12-30 | — | — | CN | disclosed |