Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14900001 | 0.78 | PTPN1 (0.37) | PTPN1 | |
| SCHEMBL13187428 | 0.76 | — | — | |
| SCHEMBL18924213 | 0.71 | — | — | |
| SCHEMBL14865123 | 0.71 | — | — | |
| SCHEMBL2531786 | 0.71 | — | — | |
| SCHEMBL12332396 | 0.68 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL18382986 | 0.67 | PTPN1 (0.36) | PTPN1 | |
| SCHEMBL5983488 | 0.67 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL8256176 | 0.67 | — | — | |
| SCHEMBL15976424 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3798214-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | Vertex Pharmaceuticals Incorporated (US) | 2021-03-31 | — | — | EP | disclosed |
| WO-2011030068-A1 | USE OF INDOLE DERIVATIVES AS NURR-1 ACTIVATORS FOR THE APPLICATION THEREOF AS A MEDICAMENT FOR THE TREATMENT OF PARKINSON'S DISEASE | LABORATOIRES FOURNIER SA (FR) | 2011-03-17 | — | — | WO | disclosed |