⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17340426 | 0.79 | — | — | |
| SCHEMBL30798646 | 0.78 | — | — | |
| SCHEMBL15196654 | 0.77 | LMNA (0.37) | — | |
| SCHEMBL28105881 | 0.77 | — | — | |
| SCHEMBL28105335 | 0.77 | — | — | |
| SCHEMBL11598282 | 0.76 | — | — | |
| SCHEMBL446703 | 0.75 | — | — | |
| SCHEMBL7939033 | 0.74 | — | — | |
| SCHEMBL28650715 | 0.74 | — | — | |
| SCHEMBL18576246 | 0.74 | HPGD (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634491-B | Polycyclic compound for inhibiting RNA helicase DHX33 | 成都开悦生命科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-114634491-A | Polycyclic compound for inhibiting RNA helicase DHX33 | 成都开悦生命科技有限公司 | 2022-06-17 | — | — | CN | disclosed |
| EP-1879910-B1 | TRIPEPTIDES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-11-09 | — | — | EP | disclosed |
| WO-2006122188-A2 | TRIPEPTIDES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-11-16 | — | — | WO | disclosed |