Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13584133 | 0.87 | CTSS (0.61) | CTSSCTSK | |
| SCHEMBL2146750 | 0.83 | CTSS (0.62) | CTSSCTSK | |
| SCHEMBL16474505 | 0.81 | CTSS (0.69) | CTSSCTSK | |
| SCHEMBL3115130 | 0.80 | CTSS (0.66) | CTSSCTSK | |
| SCHEMBL1629494 | 0.79 | CTSS (0.82) | CTSSCTSK | |
| SCHEMBL6899752 | 0.79 | CTSS (0.53) | CTSSCTSK | |
| SCHEMBL6897925 | 0.78 | CTSS (0.52) | CTSSCTSK | |
| SCHEMBL2146936 | 0.78 | CTSS (0.49) | CTSSCTSK | |
| SCHEMBL2146759 | 0.77 | CTSS (0.80) | CTSSCTSK | |
| SCHEMBL6900519 | 0.76 | CTSS (0.49) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523954-B1 | 1H-[1,2,3]TRIAZOLO[4,5-C]PYRIDINE-4- CARBONITRILE DERIVATIVES AS CATHEPSIN S INHIBITORS | MERCK SHARP & DOHME (NL) | 2014-04-16 | — | — | EP | disclosed |
| WO-2011086125-A1 | 1H-[1,2,3]TRIAZOLO[4,5-c]PYRIDINE-4-CARBONITRILE DERIVATIVES | N.V. ORGANON (NL) | 2011-07-21 | — | — | WO | disclosed |