SCHEMBL6901340

SCHEMBL6901340

CCCC(=O)OC[C@H]1O[C@@H](n2cnc(C(N)=O)n2)[C@H](O)[C@@H]1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
ADORA1 P30542 2/20 0.65
ALDH1A1 P00352 2/20 0.65
TSHR P16473 2/20 0.65
GLA P06280 1/20 0.65
EIF4E P06730 1/20 0.65
CYP3A4 P08684 1/20 0.65
TOP1 P11387 1/20 0.65
THPO P40225 1/20 0.65
PMP22 Q01453 1/20 0.65
PNP P00491 3/20 0.50
FBP1 P09467 1/20 0.39
ATIC P31939 1/20 0.39
PRKACA P17612 2/20 0.39
HINT1 P49773 2/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
SLC6A3 Q01959 1/20 0.39
TMEM97 Q5BJF2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8100029 0.87 LMNA (0.54) LMNASMN1; SMN2ADORA1ALDH1A1TSHR
SCHEMBL11805366 0.87 LMNA (0.70) LMNASMN1; SMN2ADORA1ALDH1A1TSHR
SCHEMBL14108537 0.85 LMNA (0.61) LMNASMN1; SMN2ADORA1ALDH1A1TSHR
SCHEMBL15046105 0.84 LMNA (0.70) LMNASMN1; SMN2ADORA1ALDH1A1TSHR
SCHEMBL12151510 0.84 LMNA (0.73) LMNASMN1; SMN2ADORA1ALDH1A1TSHR
SCHEMBL25520855 0.84 LMNA (0.73) LMNASMN1; SMN2ADORA1ALDH1A1TSHR
SCHEMBL13641077 0.84 LMNA (0.66) LMNASMN1; SMN2ADORA1ALDH1A1TSHR
SCHEMBL12150452 0.83 LMNA (0.79) LMNASMN1; SMN2ADORA1ALDH1A1TSHR
SCHEMBL15019611 0.83 LMNA (0.79) LMNASMN1; SMN2ADORA1ALDH1A1TSHR
SCHEMBL14108533 0.83 LMNA (0.79) LMNASMN1; SMN2ADORA1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680292-B1 STIMULATION OF NEURONAL SURVIVAL, PROLIFERATION AND NEURITE ELONGATION THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2004-01-20 US claimed
WO-2000030656-A9 NEURON STIMULATION BY RIBAVIRIN, AND ANALOGS THEREOF SALK INST FOR BIOLOGICAL STUDI (US) 2001-12-13 WO claimed
WO-2000030656-A1 NEURON STIMULATION BY RIBAVIRIN, AND ANALOGS THEREOF THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2000-06-02 WO claimed
US-3984396-A VIRICIDES ICN PHARMACEUTICALS, INC. (US) 1976-10-05 US claimed
US-6680292-B1 STIMULATION OF NEURONAL SURVIVAL, PROLIFERATION AND NEURITE ELONGATION THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2004-01-20 US disclosed
WO-2000030656-A9 NEURON STIMULATION BY RIBAVIRIN, AND ANALOGS THEREOF SALK INST FOR BIOLOGICAL STUDI (US) 2001-12-13 WO disclosed