Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.65 |
| ▸ | EIF4E | P06730 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | TOP1 | P11387 | 1/20 | 0.65 |
| ▸ | THPO | P40225 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | PNP | P00491 | 3/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 2/20 | 0.39 |
| ▸ | HINT1 | P49773 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100029 | 0.87 | LMNA (0.54) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL11805366 | 0.87 | LMNA (0.70) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL14108537 | 0.85 | LMNA (0.61) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL15046105 | 0.84 | LMNA (0.70) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL12151510 | 0.84 | LMNA (0.73) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL25520855 | 0.84 | LMNA (0.73) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL13641077 | 0.84 | LMNA (0.66) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL12150452 | 0.83 | LMNA (0.79) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL14108533 | 0.83 | LMNA (0.79) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR | |
| SCHEMBL15019611 | 0.83 | LMNA (0.79) | LMNASMN1; SMN2ADORA1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6680292-B1 | STIMULATION OF NEURONAL SURVIVAL, PROLIFERATION AND NEURITE ELONGATION | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2004-01-20 | — | — | US | claimed |
| WO-2000030656-A9 | NEURON STIMULATION BY RIBAVIRIN, AND ANALOGS THEREOF | SALK INST FOR BIOLOGICAL STUDI (US) | 2001-12-13 | — | — | WO | claimed |
| WO-2000030656-A1 | NEURON STIMULATION BY RIBAVIRIN, AND ANALOGS THEREOF | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2000-06-02 | — | — | WO | claimed |
| US-3984396-A | VIRICIDES | ICN PHARMACEUTICALS, INC. (US) | 1976-10-05 | — | — | US | claimed |
| US-6680292-B1 | STIMULATION OF NEURONAL SURVIVAL, PROLIFERATION AND NEURITE ELONGATION | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2004-01-20 | — | — | US | disclosed |
| WO-2000030656-A9 | NEURON STIMULATION BY RIBAVIRIN, AND ANALOGS THEREOF | SALK INST FOR BIOLOGICAL STUDI (US) | 2001-12-13 | — | — | WO | disclosed |