Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645833 | 0.81 | CYP3A4 (0.50) | TRPA1CYP3A4NPC1RAB9AALDH1A1 | |
| SCHEMBL30519851 | 0.81 | CYP3A4 (0.50) | TRPA1CYP3A4NPC1RAB9AALDH1A1 | |
| SCHEMBL627870 | 0.79 | CYP3A4 (0.52) | TRPA1CYP3A4NPC1RAB9AALDH1A1 | |
| SCHEMBL31115173 | 0.79 | CYP3A4 (0.52) | TRPA1CYP3A4NPC1RAB9AALDH1A1 | |
| SCHEMBL31115174 | 0.79 | CYP3A4 (0.52) | TRPA1CYP3A4NPC1RAB9AALDH1A1 | |
| SCHEMBL608937 | 0.79 | CYP3A4 (0.48) | TRPA1CYP3A4NPC1RAB9AALDH1A1 | |
| SCHEMBL27900891 | 0.78 | CYP3A4 (0.47) | TRPA1CYP3A4NPC1RAB9AALDH1A1 | |
| SCHEMBL3278219 | 0.77 | TRPA1 (0.52) | TRPA1NPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL11622256 | 0.76 | NPC1 (0.61) | TRPA1NPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL11622258 | 0.76 | NPC1 (0.61) | TRPA1NPC1RAB9AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6746562-B2 | STABLE CROSSLINKED STRUCTURE AT ROOM TEMPERATURE, THEREBY HAVING RUBBER PLASTICITY, SUFFICIENT MELT FLOWABILITY AND REPEATED CROSSLINKING FORMATION AND DISSOCIATION | THE YOKOHAMA RUBBER CO., LTD (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040059060-A1 | Thermo-reversible, crosslinkable elastomer and composition thereof | CHINO KEISUKE (JP) | 2004-03-25 | — | — | US | disclosed |