Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | DBH | P09172 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5097820 | 0.90 | CYP3A4 (0.50) | GABRA1GABRB2CYP3A4TRPA1ATM | |
| SCHEMBL11855962 | 0.85 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4KMT2AMEN1 | |
| SCHEMBL374209 | 0.85 | GABRA1 (0.56) | GABRA1GABRB2CYP3A4TRPA1ATM | |
| SCHEMBL5456903 | 0.79 | CYP3A4 (0.54) | GABRA1GABRB2CYP3A4TRPA1KMT2A | |
| SCHEMBL1133364 | 0.79 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4TRPA1ATM | |
| SCHEMBL28201284 | 0.79 | GABRA1 (0.50) | GABRA1GABRB2CYP3A4TRPA1ATM | |
| SCHEMBL30520271 | 0.78 | CYP3A4 (0.63) | GABRA1GABRB2CYP3A4TRPA1ATM | |
| SCHEMBL20145 | 0.78 | CYP3A4 (0.63) | GABRA1GABRB2CYP3A4TRPA1ATM | |
| SCHEMBL4755413 | 0.77 | ATM (0.50) | TRPA1ATMKMT2AMEN1HSP90AA1 | |
| SCHEMBL1064753 | 0.76 | GABRA1 (0.47) | GABRA1GABRB2CYP3A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6746562-B2 | STABLE CROSSLINKED STRUCTURE AT ROOM TEMPERATURE, THEREBY HAVING RUBBER PLASTICITY, SUFFICIENT MELT FLOWABILITY AND REPEATED CROSSLINKING FORMATION AND DISSOCIATION | THE YOKOHAMA RUBBER CO., LTD (JP) | 2004-06-08 | — | — | US | disclosed |
| US-20040059060-A1 | Thermo-reversible, crosslinkable elastomer and composition thereof | CHINO KEISUKE (JP) | 2004-03-25 | — | — | US | disclosed |