Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932030 | 1.00 | L3MBTL1 (0.35) | L3MBTL1KMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL1930502 | 0.91 | L3MBTL1 (0.38) | L3MBTL1KMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL1933255 | 0.91 | AAK1 (0.33) | AAK1APP | |
| SCHEMBL1903340 | 0.90 | L3MBTL1 (0.38) | L3MBTL1KMT2ALMNASMN1; SMN2TRPV1 | |
| SCHEMBL1932246 | 0.90 | L3MBTL1 (0.39) | L3MBTL1KMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL6900385 | 0.89 | L3MBTL1 (0.38) | L3MBTL1KMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL1932902 | 0.89 | L3MBTL1 (0.37) | L3MBTL1KMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL1930546 | 0.89 | L3MBTL1 (0.44) | L3MBTL1KMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL1932521 | 0.89 | L3MBTL1 (0.41) | L3MBTL1KMT2ALMNATHRBSMN1; SMN2 | |
| SCHEMBL1931845 | 0.89 | KMT2A (0.37) | L3MBTL1KMT2ALMNATHRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051165-A1 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-05 | — | — | WO | disclosed |