SCHEMBL6901565

SCHEMBL6901565

O=C=NC1CCC(N=C=O)CC1.O=C=NCCCCCCCCCCCCN=C=O

nearest known ligand 0.48

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
CYP3A4 P08684 1/20 0.40
APLNR P35414 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28238709 1.00 ALDH1A1 (0.48) ALDH1A1CYP3A4APLNR
SCHEMBL28143136 1.00 ALDH1A1 (0.48) ALDH1A1CYP3A4APLNR
SCHEMBL9775798 0.98 ALDH1A1 (0.50) ALDH1A1CYP3A4APLNR
SCHEMBL2895514 0.91 ALDH1A1 (0.41) ALDH1A1CYP3A4
Pentane SCHEMBL28123213 0.91 ALDH1A1 (0.41) ALDH1A1CYP3A4
SCHEMBL11591853 0.90 ALDH1A1 (0.65) ALDH1A1CYP3A4
SCHEMBL7590793 0.88 ALDH1A1 (0.42) ALDH1A1CYP3A4
SCHEMBL11002872 0.87 ALDH1A1 (0.38) ALDH1A1CYP3A4
SCHEMBL7781627 0.84 ALDH1A1 (0.42) ALDH1A1CYP3A4
Cyclohexane SCHEMBL28222908 0.83 ALDH1A1 (0.45) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6806340-B2 TEXTILE AND LEATHER COVERINGS; NO MONOMER SEPARATION REQUIRED BAYER AKTIENGESELLSCHAFT (DE) 2004-10-19 US disclosed
US-20030032756-A1 Polyurethane coatings, based on polyisocyanates containing uretdione and/or oxadiazinetrione groups BAYER AKTIENGESELLSCHAFT (DE) 2003-02-13 US disclosed