Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 19/20 | 0.54 |
| ▸ | TGM2 | P21980 | 19/20 | 0.54 |
| ▸ | TGM1 | P22735 | 19/20 | 0.54 |
| ▸ | TGM6 | O95932 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868569 | 0.85 | F13A1 (0.67) | F13A1TGM2TGM1TGM6 | |
| SCHEMBL1868938 | 0.79 | F13A1 (0.66) | F13A1TGM2TGM1TGM6GFER | |
| SCHEMBL1864181 | 0.74 | GFER (0.67) | F13A1TGM2TGM1TGM6GFER | |
| SCHEMBL1870053 | 0.73 | TGM2 (0.66) | F13A1TGM2TGM1GFER | |
| SCHEMBL14915863 | 0.72 | F13A1 (0.74) | F13A1TGM2TGM1TGM6 | |
| SCHEMBL1873625 | 0.72 | TGM2 (0.70) | F13A1TGM2TGM1TGM6 | |
| SCHEMBL1872968 | 0.71 | F13A1 (0.66) | F13A1TGM2TGM1TGM6GFER | |
| SCHEMBL1871105 | 0.70 | F13A1 (1.00) | F13A1TGM2TGM1TGM6 | |
| SCHEMBL1871534 | 0.70 | F13A1 (0.72) | F13A1TGM2TGM1TGM6 | |
| SCHEMBL1870961 | 0.69 | F13A1 (0.70) | F13A1TGM2TGM1TGM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060321-A1 | TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2011-05-19 | — | — | WO | disclosed |