Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 19/20 | 0.58 |
| ▸ | TGM2 | P21980 | 19/20 | 0.58 |
| ▸ | TGM1 | P22735 | 19/20 | 0.58 |
| ▸ | TGM6 | O95932 | 1/20 | 0.58 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1874743 | 0.89 | TGM2 (0.72) | F13A1TGM2TGM1TGM6TGM3 | |
| SCHEMBL14915727 | 0.79 | TGM2 (0.72) | F13A1TGM2TGM1TGM6TGM3 | |
| SCHEMBL1878169 | 0.78 | TGM2 (0.69) | F13A1TGM2TGM1TGM6TGM3 | |
| SCHEMBL6902118 | 0.77 | TGM2 (0.46) | F13A1TGM2TGM1TGM6TGM3 | |
| SCHEMBL14915749 | 0.77 | F13A1 (0.76) | F13A1TGM2TGM1TGM3 | |
| SCHEMBL1871105 | 0.74 | F13A1 (1.00) | F13A1TGM2TGM1TGM6 | |
| SCHEMBL1871356 | 0.73 | TGM2 (1.00) | F13A1TGM2TGM1TGM3EPHX2 | |
| SCHEMBL1869225 | 0.72 | F13A1 (0.67) | F13A1TGM2TGM1TGM3EPHX2 | |
| SCHEMBL1873564 | 0.66 | TGM2 (0.72) | F13A1TGM2TGM1TGM6 | |
| SCHEMBL14915308 | 0.66 | F13A1 (0.74) | F13A1TGM2TGM1TGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060321-A1 | TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2011-05-19 | — | — | WO | disclosed |