Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.39 |
| ▸ | PPARG | P37231 | 7/20 | 0.39 |
| ▸ | PPARD | Q03181 | 7/20 | 0.39 |
| ▸ | PPARA | Q07869 | 7/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27417532 | 1.00 | AKR1B1 (0.40) | AKR1B1GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL28555319 | 0.97 | AKR1B1 (0.42) | AKR1B1GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL7665901 | 0.97 | AKR1B1 (0.42) | AKR1B1GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL9295253 | 0.95 | AKR1B1 (0.40) | AKR1B1GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL15510739 | 0.88 | AKR1B1 (0.36) | AKR1B1GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL20548325 | 0.87 | GPR84 (0.48) | AKR1B1GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL27765437 | 0.87 | AKR1B1 (0.39) | AKR1B1GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL29060599 | 0.87 | GPR84 (0.48) | AKR1B1GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL29060597 | 0.87 | GPR84 (0.48) | AKR1B1GPR84PPARGPPARDPPARA | |
| Acetic Acid SCHEMBL27896694 | 0.86 | SPHK2 (0.37) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260320-B | Use of ionic polysaccharide derivatives as anti-icing coating materials | 中国科学院化学研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-115260320-A | Use of ionic polysaccharide derivatives as anti-icing coating materials | 中国科学院化学研究所 | 2022-11-01 | — | — | CN | disclosed |
| EP-0902806-B1 | FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-0902806-A1 | FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1999-03-24 | — | — | EP | disclosed |
| WO-1997045480-A1 | FLUOROELASTOMER COMPOSITIONS | DYNEON LLC (US) | 1997-12-04 | — | — | WO | disclosed |
| US-5681881-A | LOW TEMPERATURE FLEXIBILITY; AUTOMOTIVE FUEL LINES, GASKETS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-10-28 | — | — | US | disclosed |