Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595704 | 0.90 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL3481496 | 0.83 | — | — | |
| SCHEMBL10552922 | 0.80 | TSHR (0.41) | TSHRALDH1A1THRBFDPS | |
| SCHEMBL28305799 | 0.80 | TSHR (0.41) | TSHRALDH1A1THRBFDPS | |
| SCHEMBL3481963 | 0.80 | ALDH1A1 (0.30) | TSHRALDH1A1 | |
| SCHEMBL8074949 | 0.79 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL546952 | 0.78 | — | — | |
| SCHEMBL19513470 | 0.78 | ALDH1A1 (0.50) | TSHRALDH1A1LMNA | |
| SCHEMBL18869769 | 0.77 | — | — | |
| SCHEMBL18869542 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169660-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | Corsair Pharma, Inc. (US) | 2017-05-24 | — | — | EP | disclosed |
| WO-2016010538-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | Corsair Pharma, Inc. (US) | 2016-01-21 | — | — | WO | disclosed |
| WO-2004022033-A1 | METHOD AND DEVICE FOR THE CONTROLLED DELIVERY OF PARATHYROID HORMONE | MICROCHIPS, INC. (US) | 2004-03-18 | — | — | WO | disclosed |