4-(Hydroxyamino)Butanoic Acid

4-(Hydroxyamino)Butanoic Acid

SCHEMBL1655977

O=C(O)CCCNO

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-(Hydroxyamino)Butanoic Acid SCHEMBL28266183 0.97
SCHEMBL4941181 0.92
SCHEMBL39829 0.89 TSHR (0.63)
SCHEMBL6902609 0.89 TSHR (0.63)
SCHEMBL7100034 0.89 TSHR (0.63)
SCHEMBL6899587 0.89 TSHR (0.63)
SCHEMBL6900773 0.89 TSHR (0.63)
SCHEMBL20518454 0.89 TSHR (0.63)
SCHEMBL4108574 0.81
SCHEMBL112741 0.79 LMNA (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110729-A1 Primary N-hydroxylamines NIH 2004-06-10 US claimed
US-6455589-B1 AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-09-24 US claimed
JP-58177947-A None JP disclosed
JP-58164555-A None JP disclosed
JP-58177948-A None JP disclosed
CN-119219540-A Oxiracetam and key intermediate of optical isomer thereof, and preparation method and application thereof 成都百途医药科技有限公司 2024-12-31 CN disclosed
US-12043674-B2 Synthetic cyclic peptides and methods of preparation and use thereof AUBURN UNIVERSITY (US) 2024-07-23 US disclosed
CN-115843821-B Application of glyceraldehyde phosphate in preparation of preparation for improving plant disease resistance 中国农业大学 2024-04-16 CN disclosed
CN-116814678-B Application of CrUGT72B3 gene or related biological material thereof in improving plant stress resistance 青岛农业大学 2024-02-23 CN disclosed
CN-116814678-A Application of CrUGT72B3 gene or related biological material thereof in improving plant stress resistance 青岛农业大学 2023-09-29 CN disclosed
CN-114600712-B Method for promoting tomato fruit ripening and improving quality thereof 浙江大学 2023-05-05 CN disclosed
US-5739287-A BOUND ALSO TO A RECEPTOR MODULATING AGENT TO IMPEDE CELL SURFACE RECEPTOR TRAFFICKING PATHWAYS BY INHIBITING THE RECYCLING OF RECEPTORS TO THE CELL SURFACE; ANTITUMOR AND -CARCINOGENIC AGENTS; LEUKEMIA UNIVERSITY OF WASHINGTON (US) 1998-04-14 US disclosed
WO-1997014711-A9 VITAMIN B12 RECEPTOR MODULATING AGENTS AND METHODS RELATED THERETO 1997-10-02 WO disclosed
WO-1997014711-A1 VITAMIN B12 RECEPTOR MODULATING AGENTS AND METHODS RELATED THERETO RECEPTAGEN CORPORATION (US) 1997-04-24 WO disclosed
EP-0754189-A1 RECEPTOR MODULATING AGENTS AND METHODS RELATING THERETO RECEPTAGEN CORPORATION (US) 1997-01-22 EP disclosed
WO-1995027723-A1 RECEPTOR MODULATING AGENTS AND METHODS RELATING THERETO RECEPTAGEN CORPORATION (US) 1995-10-19 WO disclosed
US-4826817-A DRUG DELIVERY BROWN THOMAS E (US) 1989-05-02 US disclosed
JP-S58177948-A SEPARATION OF HYDROXYAMINOBUTYRIC ACID MITSUI TOATSU CHEM INC 1983-10-18 JP disclosed
JP-S58177947-A SEPARATION OF BETA-HYDROXY-ALPHA-AMINOBUTYRIC ACID MITSUI TOATSU CHEM INC 1983-10-18 JP disclosed
JP-S58164555-A PRODUCTION OF HYDROXYAMINOBUTYRIC ACID MITSUI TOATSU CHEM INC 1983-09-29 JP disclosed