SCHEMBL6902870

SCHEMBL6902870

C=CC[Si](C)(OC(=C)C)OC(=C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22462012 0.82 ALDH1A1 (0.30) ALDH1A1TP53TSHR
SCHEMBL2283499 0.80 HSD17B10 (0.35) ALDH1A1
SCHEMBL600083 0.72 ALDH1A1 (0.35) ALDH1A1TP53TSHR
SCHEMBL319670 0.72
SCHEMBL9576404 0.72
Ammonia Solution, Strong SCHEMBL28024868 0.70
SCHEMBL7544852 0.70
SCHEMBL9570645 0.70
SCHEMBL147872 0.70
SCHEMBL5705544 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1300440-B1 SILICONE RUBBER COMPOSITIONS FOR RUBBER CONSTRUCTION MATERIALS SHINETSU CHEMICAL CO (JP) 2017-01-04 EP disclosed
US-6770690-B2 USE IN RUBBER CONSTRUCTION MATERIALS CONTAINS DISPERSED PARTICLES HAVING A PHOTOCATALYTIC ACTIVITY. THE PARTICLES ARE SURFACE-TREATED WITH A COMPOUND THAT CAN EASILY BE DETERIORATED BY THE PHOTOCATALYTIC ACTIVITY SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-03 US disclosed
US-20030119975-A1 Silicone rubber compositions for rubber construction materials SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-06-26 US disclosed
EP-1300440-A1 Silicone rubber compositions for rubber construction materials SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-04-09 EP disclosed