Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 6/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898713 | 0.87 | TP53 (0.64) | RARBTP53TSHRNPC1LMNA | |
| SCHEMBL9697051 | 0.85 | NPC1 (0.69) | RARBTP53TSHRNPC1LMNA | |
| SCHEMBL14802207 | 0.85 | RARB (0.52) | RARBTP53TSHRNPC1LMNA | |
| SCHEMBL6899502 | 0.84 | RARB (0.69) | RARBTP53TSHRNPC1LMNA | |
| SCHEMBL7690507 | 0.83 | MAPT (0.58) | RARBTSHRNPC1LMNACYP1A2 | |
| SCHEMBL6575501 | 0.83 | TP53 (0.58) | TP53TSHRNPC1LMNACYP1A2 | |
| SCHEMBL9356366 | 0.83 | RARB (0.72) | RARBTP53TSHRNPC1LMNA | |
| SCHEMBL8943242 | 0.83 | RARB (0.72) | RARBTP53TSHRNPC1LMNA | |
| SCHEMBL9436019 | 0.83 | RARB (0.72) | RARBTP53TSHRNPC1LMNA | |
| SCHEMBL27309251 | 0.83 | TP53 (0.59) | RARBTP53TSHRNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156997-B1 | METHOD FOR PRODUCING (1,1':4'1'')-TERPHENYL COMPOUNDS | CLARIANT GMBH (DE) | 2004-04-28 | — | — | EP | disclosed |