Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898713 | 0.96 | TP53 (0.64) | TP53TSHRNPC1LMNACYP1A2 | |
| SCHEMBL5706031 | 0.93 | LTA4H (0.65) | TP53TSHRPLA2G4BFAAHLTA4H | |
| SCHEMBL10710134 | 0.91 | FAAH (0.68) | TP53TSHRNPC1LMNACYP1A2 | |
| SCHEMBL10708325 | 0.89 | THRB (0.56) | LMNACYP1A2CYP2D6CYP3A4SMN1; SMN2 | |
| SCHEMBL10709087 | 0.88 | FAAH (0.54) | TP53TSHRNPC1LMNACYP1A2 | |
| SCHEMBL5705994 | 0.88 | FAAH (0.70) | TP53TSHRNPC1LMNAPLA2G4B | |
| SCHEMBL27309251 | 0.88 | TP53 (0.59) | TP53TSHRNPC1LMNACYP1A2 | |
| SCHEMBL10707014 | 0.88 | FAAH (0.65) | TP53TSHRNPC1LMNACYP1A2 | |
| SCHEMBL10711366 | 0.87 | THRB (0.57) | TP53TSHRNPC1LMNACYP1A2 | |
| SCHEMBL10708962 | 0.87 | CYP1A1 (0.53) | NPC1LMNACYP1A2CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412411-A2 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2004-04-28 | — | — | EP | disclosed |
| WO-2003008481-A2 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-01-30 | — | — | WO | disclosed |
| US-6491774-B2 | Method for preparing an improved liquid crystal clinical thermometer | MEDICAL INDICATORS, INC. | 2002-12-10 | — | — | US | disclosed |
| US-20020074074-A1 | Method for preparing an improved liquid crystal clinical thermometer | MEDICAL INDICATORS, INC. | 2002-06-20 | — | — | US | disclosed |
| US-6284078-B1 | Method for preparing an improved liquid crystal clinical thermometer | MEDICAL INDICATORS, INC. | 2001-09-04 | — | — | US | disclosed |
| US-6143917-A | FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD | UBE INDUSTRIES, LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902014-A1 | PROCESS FOR PRODUCING ARYL CARBAMATES | UBE INDUSTRIES LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |