Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916650 | 0.76 | KMT2A (0.52) | KMT2AHPGDCA1CA2MMP1 | |
| SCHEMBL4990043 | 0.76 | KMT2A (0.52) | KMT2AHPGDCA1CA2MMP1 | |
| SCHEMBL27801072 | 0.76 | KMT2A (0.52) | KMT2AHPGDCA1CA2MMP1 | |
| SCHEMBL6236220 | 0.76 | TSHR (0.42) | KMT2AHPGDTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL6234894 | 0.76 | TSHR (0.50) | KMT2AHPGDFAAHHTTTSHR | |
| SCHEMBL6240573 | 0.75 | HPGD (0.41) | KMT2AHPGDCA1CA2CA9 | |
| SCHEMBL6232558 | 0.75 | HPGD (0.44) | KMT2AHPGDCA2CA9FAAH | |
| SCHEMBL11698920 | 0.75 | HPGD (0.60) | KMT2AHPGDCA1CA2MMP1 | |
| SCHEMBL21067451 | 0.74 | ALPI (0.51) | KMT2ACA1CA2CA9PRSS1 | |
| SCHEMBL4313869 | 0.74 | ALPI (0.51) | KMT2ACA1CA2CA9PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6682916-B2 | CHEMICAL INTERMEDIATE FOR DRUGS; REDUCTION USING ENZYME | KANEKA CORPORATION (JP) | 2004-01-27 | — | — | US | disclosed |
| EP-1298119-A1 | CHLOROHYDROXYACETONE DERIVATIVE AND PROCESS FOR PRODUCING OPTICALLY ACTIVE CHLOROPROPANEDIOL DERIVATIVE FROM THE SAME | KANEKA CORPORATION (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-20020160398-A1 | Chlorohydroxyacetone derivative and process for producing optically active chloropropanediol derivative from the same | KANEKA CORPORATION (JP) | 2002-10-31 | — | — | US | disclosed |