SCHEMBL6232558

SCHEMBL6232558

CC(C)COC(=O)CC(O)COS(=O)(=O)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.44
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.40
ADRB2 P07550 2/20 0.39
ADRB1 P08588 2/20 0.39
ADRB3 P13945 2/20 0.39
FPR1 P21462 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KMT2A Q03164 1/20 0.38
RAB9A P51151 1/20 0.38
KDM4E B2RXH2 2/20 0.36
FAAH O00519 1/20 0.36
LMNA P02545 1/20 0.35
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
SLC15A1 P46059 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6236220 0.88 TSHR (0.42) HPGDALDH1A1TSHRHSD17B10KMT2A
SCHEMBL6234894 0.86 TSHR (0.50) HPGDALDH1A1TSHRADRB2ADRB1
SCHEMBL6238994 0.82 HPGD (0.42) HPGDALDH1A1TSHRFPR1HSD17B10
SCHEMBL6240573 0.82 HPGD (0.41) HPGDALDH1A1TSHRADRB2ADRB1
SCHEMBL6241318 0.82 RAB9A (0.45) HPGDALDH1A1TSHRADRB2ADRB1
SCHEMBL10916650 0.80 KMT2A (0.52) HPGDALDH1A1TSHRFPR1HSD17B10
SCHEMBL6903089 0.75 KMT2A (0.46) HPGDTSHRHSD17B10KMT2ARAB9A
SCHEMBL6233361 0.74 TSHR (0.35) HPGDALDH1A1TSHR
SCHEMBL28249350 0.72 TSHR (0.56) HPGDALDH1A1TSHRADRB2ADRB1
SCHEMBL4753848 0.71 KMT2A (0.49) HPGDALDH1A1TSHRFPR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005005375-A1 METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS LANXESS DEUTSCHLAND GMBH (DE) 2005-01-20 WO claimed
WO-2005005375-A1 METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTERS LANXESS DEUTSCHLAND GMBH (DE) 2005-01-20 WO disclosed