SCHEMBL6903182

SCHEMBL6903182

O=C1C=Cc2nnncc2C1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.40
GSK3B P49841 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28513579 0.71 GSK3A (0.40) GSK3AGSK3B
SCHEMBL10373645 0.69 GSK3A (0.39) GSK3AGSK3B
SCHEMBL5285232 0.69 GSK3A (0.39) GSK3AGSK3B
SCHEMBL29419946 0.69 GSK3A (0.39) GSK3AGSK3B
SCHEMBL15760108 0.63 GSK3A (0.36) GSK3AGSK3B
SCHEMBL15760112 0.63 GSK3A (0.36) GSK3AGSK3B
SCHEMBL4564153 0.62 GSK3A (0.40) GSK3AGSK3B
SCHEMBL277815 0.61
SCHEMBL2779620 0.61 GSK3A (0.39) GSK3AGSK3B
SCHEMBL30482807 0.61 GSK3A (0.39) GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1223924-A4 USE OF CSAIDS IN RHINOVIRUS INFECTION SMITHKLINE BEECHAM CORP (US) 2004-07-14 EP disclosed
EP-1223924-A2 USE OF CSAIDS IN RHINOVIRUS INFECTION SmithKline Beecham Corporation (US) 2002-07-24 EP disclosed
WO-2001019322-A2 USE OF CSAIDS IN RHINOVIRUS INFECTION SMITHKLINE BEECHAM CORPORATION (US) 2001-03-22 WO disclosed