Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloromethane SCHEMBL248726 | 0.97 | CYP3A4 (0.80) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL236600 | 0.90 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL3710821 | 0.90 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL224846 | 0.90 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL4718125 | 0.90 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL3931585 | 0.90 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL5968399 | 0.90 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL201704 | 0.90 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL22558063 | 0.90 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL1747083 | 0.90 | TDP1 (0.92) | CYP3A4TDP1ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988331-B1 | METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS | PROMERUS LLC (US) | 2004-09-01 | — | — | EP | disclosed |
| US-6265506-B1 | AMORPHOUS COPOLYMERS | THE B. F. GOODRICH COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-0988331-A1 | METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS | THE B.F. GOODRICH COMPANY (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056839-A1 | METHOD FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE/NORBORNENE-TYPE MONOMERS WITH CATIONIC PALLADIUM CATALYSTS | THE B.F. GOODRICH COMPANY (US) | 1998-12-17 | — | — | WO | disclosed |