Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloromethane SCHEMBL6903208 | 0.97 | CYP3A4 (0.75) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Carbon Tetrachloride SCHEMBL313349 | 0.90 | CYP3A4 (0.75) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL81285 | 0.90 | TDP1 (0.86) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL3181354 | 0.90 | TDP1 (0.86) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL1951204 | 0.90 | TDP1 (0.86) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL9420677 | 0.90 | TDP1 (0.86) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL561726 | 0.90 | TDP1 (0.86) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL5028587 | 0.89 | TDP1 (1.00) | CYP3A4TDP1ESR1ESR2KDM4E | |
| Benzene SCHEMBL6890099 | 0.89 | TDP1 (1.00) | CYP3A4TDP1ESR1ESR2KDM4E | |
| SCHEMBL101 | 0.89 | TDP1 (1.00) | CYP3A4TDP1ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111378456-B | Negative liquid crystal compound containing terminal alkenyl and synthetic method thereof | 江苏和成新材料有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-111378456-A | Negative liquid crystal compound containing terminal alkenyl and synthetic method thereof | 江苏和成新材料有限公司 | 2020-07-07 | — | — | CN | claimed |
| CN-103086848-B | Dicyclohexylalkyl ether terminal olefines liquid crystal compound and preparation method thereof | YANTAI DERUN LIQUID CRYSTAL MATERIALS CO LTD | 2014-09-03 | — | — | CN | claimed |
| US-20130165696-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | ACTAVIS GROUP PTC EHF (IS) | 2013-06-27 | — | — | US | claimed |
| EP-2588441-A2 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | Actavis Group Ptc Ehf (IS) | 2013-05-08 | — | — | EP | claimed |
| CN-103086848-A | Dicyclohexylalkyl ether terminal olefines liquid crystal compound and preparation method thereof | YANTAI DERUN LIQUID CRYSTAL MATERIALS CO LTD | 2013-05-08 | — | — | CN | claimed |
| WO-2012001531-A2 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | ACTAVIS GROUP PTC EHF (IS) | 2012-01-05 | — | — | WO | claimed |
| US-6432616-B1 | Water soluble polymer and photoresist composition containing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2002-08-13 | — | — | US | claimed |
| CN-114702184-B | High-salt high-organic matter wastewater treatment device and method | 西安瑞联新材料股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116422376-A | Platinum-ionic liquid complex catalyst for catalyzing hydrochlorination of acetylene as well as preparation method and application thereof | 石河子大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-111378456-B | Negative liquid crystal compound containing terminal alkenyl and synthetic method thereof | 江苏和成新材料有限公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-114702184-A | High-salt high-organic-matter wastewater treatment device and method | 西安瑞联新材料股份有限公司 | 2022-07-05 | — | — | CN | disclosed |
| EP-3275924-B1 | TWO-PACK TYPE EPOXY RESIN COMPOSITION FOR FIBER-REINFORCED COMPOSITE MATERIAL, AND FIBER-REINFORCED COMPOSITE MATERIAL | TORAY INDUSTRIES (JP) | 2021-11-24 | — | — | EP | disclosed |
| US-10717831-B2 | Two-component type epoxy resin composition for fiber-reinforced composite material, and fiber-reinforced composite material | TORAY INDUSRIES, INC. (JP) | 2020-07-21 | — | — | US | disclosed |
| US-4546106-A | ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1985-10-08 | — | — | US | disclosed |
| US-4355034-A | Ethenyl derivatives of mercaptoalkylpyridines as anti-inflammatory agents | MERCK & CO., INC. (US) | 1982-10-19 | — | — | US | disclosed |
| US-4217352-A | ANTIARTHRITIC AGENT | MERCK & CO., INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4144342-A | ANTIARTHRITIC AND ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1979-03-13 | — | — | US | disclosed |
| US-4061759-A | ANTIINFLAMMATORY, ARTHRITIS | MERCK & CO., INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-4053606-A | ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | MERCK & CO., INC. (US) | 1977-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165696-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PHENYLCYCLOPROPYLAMINE DERIVATIVES AND USE THEREOF FOR PREPARING TICAGRELOR | THPO, P2RY4, TBXA2R | CYP3A4 28/4885TDP1 1304/4885ESR1 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.