SCHEMBL6903418

SCHEMBL6903418

CCOC(C)OC(=O)c1ccccc1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.57
TSHR P16473 3/20 0.49
ALOX15 P16050 1/20 0.45
SCN1A P35498 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42
LMNA P02545 2/20 0.41
KDM4E B2RXH2 4/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
RECQL P46063 1/20 0.41
POLB P06746 2/20 0.40
MAPT P10636 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HPGD P15428 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5042420 0.93 TSHR (0.55) ALDH1A1TSHRSCN1ASCN2ASCN3A
Phthalic Acid SCHEMBL321766 0.88 ALDH1A1 (0.54) ALDH1A1TSHRALOX15LMNAKDM4E
SCHEMBL17798238 0.85 TSHR (0.50) ALDH1A1TSHRSCN1ASCN2ASCN3A
SCHEMBL3679498 0.85 ALDH1A1 (0.63) ALDH1A1TSHRLMNAKDM4EKMT2A
Phthalic Acid SCHEMBL2420682 0.85 ALDH1A1 (0.50) ALDH1A1TSHRALOX15LMNAKDM4E
SCHEMBL11551260 0.84 ALDH1A1 (0.51) ALDH1A1TSHRALOX15SCN1ASCN2A
SCHEMBL17798219 0.84 TSHR (0.49) ALDH1A1TSHRSCN1ASCN2ASCN3A
SCHEMBL7172984 0.83 TSHR (0.53) ALDH1A1TSHRALOX15KDM4EKMT2A
SCHEMBL27383020 0.83 ALDH1A1 (0.61) ALDH1A1TSHRKDM4EKMT2AMEN1
SCHEMBL21891536 0.82 TSHR (0.44) ALDH1A1TSHRSCN1ASCN2ASCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016040434-A1 CELLULOSE ESTER PLASTICS AND METHODS AND ARTICLES RELATING THERETO CELANESE ACETATE LLC (US) 2016-03-17 WO claimed
EP-0586575-A1 DEGRADABLE CELLULOSE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1994-03-16 EP claimed
WO-1992020738-A1 DEGRADABLE CELLULOSE POLYMERS BATTELLE MEMORIAL INSTITUTE (US) 1992-11-26 WO claimed
CN-108699296-A Lonitrile copolymer rubber composition, bridging property rubber composition and rubber cross object 日本瑞翁株式会社 2018-10-23 CN disclosed
CN-108333288-A A kind of method that gas chromatography tandem mass spectrometry is used to detect 18 kinds of plasticisers in white wine 绿城农科检测技术有限公司 2018-07-27 CN disclosed
CN-107922551-A The high saturated copolymer rubber of nitrile group-containing, bridging property rubber composition and rubber cross thing 日本瑞翁株式会社 2018-04-17 CN disclosed
WO-2016040427-A1 CELLULOSE ESTER PLASTICS AND METHODS AND ARTICLES RELATING THERETO CELANESE ACETATE LLC (US) 2016-03-17 WO disclosed
WO-2016040434-A1 CELLULOSE ESTER PLASTICS AND METHODS AND ARTICLES RELATING THERETO CELANESE ACETATE LLC (US) 2016-03-17 WO disclosed
US-6730724-B1 ADDING TO COMPOSITION COMPRISING PARTIALLY OR COMPLETELY DESTRUCTURISED AND/OR COMPLEXED STARCH, POLYSACCHARIDE ESTER AND A PLASTICIZER, AN ADDITIVE WHICH INCREASES AND MAINTAINS A PH OF 4 OR MORE NOVAMONT S.P.A. (IT) 2004-05-04 US disclosed
US-20030215506-A1 Methods and compositions for enhancement of creatine transport KUHRTS ERIC H (US) 2003-11-20 US disclosed
EP-0620929-B1 PHOTOGRAPHIC DISPERSION EASTMAN KODAK CO (US) 2003-10-01 EP disclosed
EP-1109858-B1 BIODEGRADABLE COMPOSITIONS COMPRISING STARCH AND POLYSACCHARIDE ESTERS NOVAMONT SPA (IT) 2003-04-23 EP disclosed
EP-1109858-A1 BIODEGRADABLE COMPOSITIONS COMPRISING STARCH AND POLYSACCHARIDE ESTERS NOVAMONT S.p.A. (IT) 2001-06-27 EP disclosed
WO-2000012616-A1 BIODEGRADABLE COMPOSITIONS COMPRISING STARCH AND POLYSACCHARIDE ESTERS NOVAMONT S.P.A. (IT) 2000-03-09 WO disclosed
US-5468604-A Particle growth inhibition EASTMAN KODAK COMPANY (US) 1995-11-21 US disclosed
EP-0620929-A1 PHOTOGRAPHIC DISPERSION EASTMAN KODAK COMPANY (US) 1994-10-26 EP disclosed
WO-1994011784-A1 PHOTOGRAPHIC DISPERSION EASTMAN KODAK COMPANY (US) 1994-05-26 WO disclosed
US-5068233-A For treatment of asthma, antiallergens or antihistamines ASTA PHARMA AKTIENGESELLSCHAFT (DE) 1991-11-26 US disclosed
WO-1986001521-A1 AN ADDITIVE COMPOSITION FOR INCREASING THE CONDUCTIVITY OF AN ORGANIC POLYMER, AN ACTIVE HYDROGEN-CONTAINING COMPOSITION CONTAINING THE ADDITIVE COMPOSITION, AND AN ORGANIC POLYMER COMPOSITION CONTAINING THE ADDITIVE COMPOSITION THE DOW CHEMICAL COMPANY (US) 1986-03-13 WO disclosed
US-3974080-A PHOSPHORIC ACID ESTER UNION CARBIDE CORPORATION (US) 1976-08-10 US disclosed