SCHEMBL690344

SCHEMBL690344

SCCSCCSCC(S)CS

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
HTT P42858 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28007315 1.00 NR1I2 (0.32) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL4952898 1.00 NR1I2 (0.32) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL21753876 1.00 NR1I2 (0.32) NR1I2ALDH1A1LMNACYP1A2HTT
SCHEMBL6051707 0.95
SCHEMBL6051709 0.95
SCHEMBL21753884 0.93
SCHEMBL19097572 0.90
SCHEMBL29042050 0.87
SCHEMBL24098254 0.87
SCHEMBL5078151 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120238660-A1 METHOD FOR DYEING A PLASTIC SUBSTRATE OF HIGH REFRACTIVE INDEX AND SUBSTRATE OBTAINED BY THIS METHOD ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2012-09-20 US claimed
EP-2319981-B1 Method for dyeing a plastic substrate of high refractive index ESSILOR INT (FR) 2012-02-29 EP claimed
WO-2011058460-A1 METHOD FOR DYEING A PLASTIC SUBSTRATE OF HIGH REFRACTIVE INDEX AND SUBSTRATE OBTAINED BY THIS METHOD Essilor International (Compagnie Générale d'Optique) (FR) 2011-05-19 WO claimed
EP-2319981-A1 Method for dyeing a plastic substrate of high refractive index and substrate obtained by this method ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) 2011-05-11 EP claimed
US-20250101202-A1 ISOCYANATE COMPOSITION AND OPTICAL COMPOSITION Hanwha Solutions Corporation (KR) 2025-03-27 US disclosed
WO-2024052724-A1 COATING KIT AND METHOD FOR REPAIR AND/OR RECONSTITUTION OF RUBBER AND/OR METAL WORN AREAS BERTECH PANAMÁ S.A. (PA) 2024-03-14 WO disclosed
CN-109575217-A Polymerizable composition for optical material SKC株式会社 2019-04-05 CN disclosed
US-20120238660-A1 METHOD FOR DYEING A PLASTIC SUBSTRATE OF HIGH REFRACTIVE INDEX AND SUBSTRATE OBTAINED BY THIS METHOD ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE) (FR) 2012-09-20 US disclosed
EP-2319981-B1 Method for dyeing a plastic substrate of high refractive index ESSILOR INT (FR) 2012-02-29 EP disclosed
WO-2011058460-A1 METHOD FOR DYEING A PLASTIC SUBSTRATE OF HIGH REFRACTIVE INDEX AND SUBSTRATE OBTAINED BY THIS METHOD Essilor International (Compagnie Générale d'Optique) (FR) 2011-05-19 WO disclosed
EP-2319981-A1 Method for dyeing a plastic substrate of high refractive index and substrate obtained by this method ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) 2011-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238660-A1 METHOD FOR DYEING A PLASTIC SUBSTRATE OF HIGH REFRACTIVE INDEX AND SUBSTRATE OBTAINED BY THIS METHOD ALDH1A2, MKI67, RPS21 NR1I2 66/4885ALDH1A1 85/4885LMNA 3506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.